A case of nonsystemic vasculitic neuropathy with spondylosis deformans in an 84-year-old woman

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  • Yamada Megumi
    Department of Neurology and Geriatrics, Gifu University Graduate School of Medicine
  • Tanaka Yuji
    Department of Neurology and Geriatrics, Gifu University Graduate School of Medicine
  • Kimura Akio
    Department of Neurology and Geriatrics, Gifu University Graduate School of Medicine
  • Koumura Akihiro
    Department of Neurology and Geriatrics, Gifu University Graduate School of Medicine
  • Hayashi Yuichi
    Department of Neurology and Geriatrics, Gifu University Graduate School of Medicine
  • Hozumi Isao
    Department of Neurology and Geriatrics, Gifu University Graduate School of Medicine
  • Koike Haruki
    Department of Neurology, Nagoya University Graduate School of Medicine
  • Sobue Gen
    Department of Neurology, Nagoya University Graduate School of Medicine
  • Inuzuka Takashi
    Department of Neurology and Geriatrics, Gifu University Graduate School of Medicine

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Other Title
  • 変形性脊椎症を有する高齢者に発症したnonsystemic vasculitic neuropathyの1例
  • 症例報告 変形性脊椎症を有する高齢者に発症したnonsystemic vasculitic neuropathyの1例
  • ショウレイ ホウコク ヘンケイセイ セキツイショウ オ ユウスル コウレイシャ ニ ハッショウ シタ nonsystemic vasculitic neuropathy ノ 1レイ

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Abstract

We report an 84-year-old woman with left lower limb muscle weakness and numbness who also had weakness in her right lower limb, which showed spontaneous partial improvement. Neurological examination revealed lower extremity weakness and sensory disturbance in all modalities, predominantly distally on the left side. Laboratory studies yielded normal results, except for a slightly high erythrocyte sedimentation rate. Nerve conduction studies showed axonal neuropathy in the right tibial nerve, and loss of action potentials in other lower limb nerves. Histological study of the left sural nerve revealed mainly loss of axons and differences in the density of fascicules in the axons. In addition, inflammatory cells infiltrated around small blood vessels. Therefore, we diagnosed nonsystemic vasculitic neuropathy.<br> Magnetic resonance imaging revealed that she also had spondylosis deformans and radiculopathy, which was more difficult to differentiate. Neural biopsy was important for diagnosis.<br>

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