Anticancer Effect of Alkaline Reduced Water(International Conference on Mind Body Science : Physical and Physiological Approach joint with The Eighteenth Symposium on Life Information Science)

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Author(s)

    • LEE Kyu-Jae
    • Dept. of Parasitology, Wonju College of Medicine, Yonsei Univ.:Institute of Basic Medical Sciences, Wonju College of Medicine, Yonsei Univ.
    • PARK Seung-Kyu
    • Dept. of Parasitology, Wonju College of Medicine, Yonsei Univ.:Institute of Basic Medical Sciences, Wonju College of Medicine, Yonsei Univ.
    • KIM Jae-Won
    • Dept. of Parasitology, Wonju College of Medicine, Yonsei Univ.
    • RYANG Young-Suk
    • Dept. of Biomedical Laboratory Science and Institute of Health Science, College of Health Science, Yonsei Univ.
    • KIM Geun-Ha
    • Dept. of Parasitology, Wonju College of Medicine, Yonsei Univ.
    • KIM Soo-Kie
    • Institute of Basic Medical Sciences, Wonju College of Medicine, Yonsei Univ.:Dept. of Microbiology, Wonju College of Medicine, Yonsei Univ.
    • KIM Hyun-Won
    • Institute of Basic Medical Sciences, Wonju College of Medicine, Yonsei Univ.:Dept. of Biochemistry, Wonju College of Medicine, Yonsei Univ.

Abstract

Certain minerals can produce alkaline reduced water with high pH and low oxidation-reduction potential (ORP) when dissolved in water. Alkaline reduced water (ARW) showed significant anticancer effect. When B16 melanoma cells were inoculated subcutaneously and intra-peritoneally, C56BL/6 mice fed with ARW showed tumor growth delay and the survival span was significantly lengthened. ARW also showed the inhibition of metastasis by reducing the numbers of B16 melanoma colonies when injected through tail vein. The amount of reactive oxygen species (ROS) was very reduced when fed with ARW except for spleen, which is a major organ for immunity. Even for normal mice, ARW intake invoked systemic cytokines, such as, Th1 (IFN-γ, IL-12) and Th2 (IL-4, IL-5), suggesting strong immuno-modulation effect. Both ROS scavenging effect and immuno-modulation effect might be responsible for anticancer effect of alkaline reduced water.

Journal

  • Journal of International Society of Life Information Science

    Journal of International Society of Life Information Science 22(2), 302-305, 2004

    International Society of Life Information Science

Codes

  • NII Article ID (NAID)
    110001080324
  • Text Lang
    ENG
  • ISSN
    1341-9226
  • Data Source
    NII-ELS  J-STAGE 
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