自律神経失調症状を伴った呼吸器疾患患者の心電図R-R間隔について Coefficient of Variation of R-R Intervals in Patients of Pulmanary Diseases with Autonomic Dystonia
We examined coefficient of variation of R-R intervals (CR_<R-R>) in order to know autonomic nervous function in patients with pulmonary diseases. We also examined the effects of Tofisopam on autonomic nervous function. (1) %CV_<R-R> at rest was decreased in patient groups of autonomic dystonia type and psyhosomatic disease type which were classfied by Toho Medical Index (TMI), a questionnaire which examines the tendency of autonomic dystonia. (2) %CV_<R-R> was increased at standing position in patients without autonomic dystonia, but %CV_<R-R> at standing position was not shown the difference with that at rest in patients with autonomic dystonia. (3) %CV_<R-R> was increased in patients whowere administered Tofisopam, but decreaased in patients who were not administered Tofisopam, but decreased in patients who were not administered to fisopam. (4) %CV_<R-R> was increased in non-asthmatic patients who were administered Tofisopam, but decreased in asthmatic patients who were administered Tofisopam. The opposite response to Tofisopam in asthmatic patients may indicate the different autonomic dysregulation in bronchial asthms.
心身医学 31(4), 305-310, 1991