GENE DELIVERY INTO THE CHICKEN EMBRYO BY USING REPLICATION-COMPETENT RETROVIRAL VECTORS

Access this Article

Search this Article

Author(s)

Abstract

Rous sarcoma virus (RSV)-derived retroviral vectors have allowed for efficient gene transfer into the chicken embryo which is a classical model for studying vertebrate development. Current evidence reveals that this method can be used for regionally restricted expression, inducible expression, and for interfering with endogenous gene function, suggesting that gain-of-function and loss-of-function strategies for specific genes can be achieved spatially and temporally in the avian embryo. Thus, retroviral-mediated gene transfer into the chicken embryo coupled with a wide variety of strategies is now an important tool to address specific biological questions in the vertebrate.

Journal

  • FUKUSHIMA JOURNAL OF MEDICAL SCIENCE

    FUKUSHIMA JOURNAL OF MEDICAL SCIENCE 50(2), 37-46, 2004-12-01

    The Fukushima Society of Medical Science

References:  25

Codes

  • NII Article ID (NAID)
    110001234301
  • NII NACSIS-CAT ID (NCID)
    AA0065246X
  • Text Lang
    ENG
  • Article Type
    ART
  • ISSN
    00162590
  • Data Source
    CJP  NII-ELS  IR  J-STAGE 
Page Top