A Clinicopathological Study on Primary Carcinoma of the Duodenum.

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  • 原発性十二指腸癌の臨床病理学的検討

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Abstract

The incidence of primary duodenal cancer is low among digestive tract cancers, but since it is often diag-nosed a few considerable progression, prognosis is poor. We clinicopathologically examined for 20 patients un-dergoing resection for primary duodenal cancer. Pancreatoduodenectomy numbered 15, partial duodenal ex-cision numbered 3, and pancreatoduodenectomy with preservation of the pyloric ring numbered 2 cases. Mu-ral invasion into the pancreas was observed in 14 cases and metastasis to lymph nodes in 15. Cumulative 5-year survival was 30%. Statistical analysis revealed 4 prognotic indicators of the extent of mural invasion, me-tastasis to lymph nodes, histological classification, and invasion of veins. Pancreatoduodenectomy with preser-vation of the pyloric ring acompanied by resection of the second group of lymph nodes was the standard mode for primary duodenal cancer. Pancreatoduodenectomy was required when the degree of invasion of the stomach was high, and partial duodenal excision was sufficient to radically cure early cancer with invasion of the mucosa but no metastasis to lymph nodes.

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