透析アミロイドーシスによる小腸穿孔の1例

  • 辻 孝
    First Department of Surgery, Nagasaki University School of Medicine
  • 澤井 照光
    First Department of Surgery, Nagasaki University School of Medicine
  • 柴崎 信一
    First Department of Surgery, Nagasaki University School of Medicine
  • 七島 篤志
    First Department of Surgery, Nagasaki University School of Medicine
  • 地引 政晃
    First Department of Surgery, Nagasaki University School of Medicine
  • 山口 広之
    First Department of Surgery, Nagasaki University School of Medicine
  • 安武 亨
    First Department of Surgery, Nagasaki University School of Medicine
  • 中越 享
    First Department of Surgery, Nagasaki University School of Medicine
  • 綾部 公懿
    First Department of Surgery, Nagasaki University School of Medicine
  • 安倍 邦子
    Department of Pathology, Nagasaki University Hospital

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タイトル別名
  • A Case Report of Intestinal Perforation Causing by Dialysis-Related Amyloidosis

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We experienced a case with an intestinal perforation resulting from dialysisrelated amyloidosis. A fiftysixyear old women who had been receiving hemodialysis for twenty-three years underwent an operation for bilateral carpal tunnel syndrome and destructive spondyloarthropathy. She had experienced the onset of diarrhea four months earlier, and was operated on for perforative peritonitis. The middle part of the small intestine contained a 16×8mm hole. Partial resection of the small bowel and end-to-end anastomosis was performed. A pathological examination revealed an amyloid deposit in a perivascular area of the submucosal layer, and immunohistochemistry for β2-microglobulin was positive. She was diagnosed as having dialysisrelated amyloidosis. Anastomotic leakage occurred early during the post-operative day. She was died five months later because of a sepsis.

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