Activity changes in the open-field test related to loss of rat molar occlusal support

DOI 被引用文献4件 参考文献23件
  • Okuda Keiji
    Graduate School of Dentistry (Removable Prosthodontics and Occlusion), Osaka Dental University
  • Narita Mitsutoshi
    Department of Removable Prosthodontics and Occlusion, Osaka Dental University
  • Yamamoto Satsuki
    Department of Removable Prosthodontics and Occlusion, Osaka Dental University
  • Inoue Hiroshi
    Department of Removable Prosthodontics and Occlusion, Osaka Dental University
  • Sakuma Yasushi
    Department of Anesthesiology, Osaka Dental University

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We investigated the influence of various types of loss of molar occlusal support on exploratory and emotional behavior of seven-week-old rats. The animals were divided into four groups : one with all maxillary molars extracted, one with only unilateral maxillary molars extracted, one with the maxillary first and second molars extracted, and a control group where anesthesia was performed without tooth extraction. An open-field test, where the animals were used to investigate behavioral changes, was performed 1, 5, and 8 weeks after tooth extraction. There were no changes in exploratory or emotional behaviors among the 4 groups 1, 5, and 8 weeks after tooth extraction. These results suggest that the loss of molar occlusal support had no influence on activity or emotions of the rats 8 weeks after tooth extraction. (J Osaka Dent Univ 2004; 38: 83-88)

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