Additional survey on genotoxicity of natural anthraquinones in the hepatocyte primary culture/DNA repair assay.

• MORI Hideki

• YOSHIMI Naoki

• IWATA Hitoshi

• TANAKA Takuji

• KAWAI Kiyoshi

• SANKAWA Ushio

抄録

Genotoxicity of fungal anthraquinones of islandicin, iridoskyrin and (-) rubroskyrin, and a colorant of insect origin, cochineal and its component, carminic acid, an anthraquinone, was examined in the hepatocyte primary culture/DNA repair test. The results were compared with that of versicolorin A, an anthraquinone with bisfuran ring, which had been proved to be genotoxic on this assay. All of these anthraquinones, differently from versicolorin A did not show clear response of DNA repair. The results suggest that these agents are not genotoxic carcinogens.

収録刊行物

• Ｔｈｅ　Ｊｏｕｒｎａｌ　ｏｆ　Ｔｏｘｉｃｏｌｏｇｉｃａｌ　Ｓｃｉｅｎｃｅｓ

  Ｔｈｅ　Ｊｏｕｒｎａｌ　ｏｆ　Ｔｏｘｉｃｏｌｏｇｉｃａｌ　Ｓｃｉｅｎｃｅｓ 13 (3), 161-166, 1988

  一般社団法人　日本毒性学会

キーワード

• unscheduled DNA synthesis

詳細情報

• CRID: 1390001204900411008
• NII論文ID: 110001804691
• NII書誌ID: AN00002808
• DOI: 10.2131/jts.13.161
• ISSN: 18803989
• ISSN: 03881350
• PubMed: 3193483
• Web Site: http://www.jstage.jst.go.jp/article/jts1976/13/3/13_3_161/_pdf
• Web Site: https://search.jamas.or.jp/link/ui/1989216369
• 本文言語コード: en
• データソース種別:
  • JaLC
  • Crossref
  • PubMed
  • CiNii Articles
• 抄録ライセンスフラグ: 使用不可