アトピー性皮膚炎に対する草津温泉療法の効果

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  • 久保田 一雄
    群馬大学医学部附属病院草津分院内科リハビリテーション部
  • 町田 泉
    群馬大学医学部附属病院草津分院内科リハビリテーション部
  • 田村 耕成
    群馬大学医学部附属病院草津分院内科リハビリテーション部
  • 倉林 均
    群馬大学医学部附属病院草津分院内科リハビリテーション部
  • 白倉 卓夫
    群馬大学医学部附属病院草津分院内科リハビリテーション部

書誌事項

タイトル別名
  • Effects of Balneotherapy on Atopic Dermatitis at Kusatsu.
  • アトピーセイ ヒフエン ニ タイスル クサツ オンセン リョウホウ ノ コウカ

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抄録

From June 1990 to May 1995, 46 patients with atopic dermatitis (31 males and 15 females, 25±11 years) were admitted to our hospital to receive balneotherapy using Kusatsu hot-spring water. The atopic dermatitis in all but 4 cases occurred while the patients were still under 20 and had been refractory to various treatments including steroid ointment therapy over a long period of time. A week's observation allowing only a hot fresh water shower to remove environmental factors, resulting in no change in their skin symptoms and pruritus, was followed by taking a 10-minute 40-42°C hot-spring bath 1-2 times daily for 3-28 consecutive weeks. The pH of the hot-spring water is 2.0 and its main components are aluminium, sulphates and chlorides. The skin symptoms of 32 out of 46 cases were improved through hot hot-spring bathing and furthermore pruritus was improved in 18 out of the 32 cases. The improvement of skin symptoms was supported by a significant decrease in serum LDH levels. In contrast, pruritus was not inproved in the remaining 14 cases who showed no changes in skin symptoms and serum LDH levels. Moreover, changes in the number of Staphylococcus aureus on the skin surface were examined before and after balneotherapy. In the 21 cases examined whose skin symptoms were improved, many Staphylococci aureus were detected in 15 of the cases but not in the other 6 cases before starting the balneotherapy. However, they disappeared in 13 out of the 15 cases and decreased in the remaining 2 cases through the balneotherapy. On the other hand, the number of Staphylococcus aureus on the skin surface was not changed in 6 out of the 7 cases whose skin symptoms were not improved. The mechanisms of the improvement of skin symptoms through hot hot-spring bathing may be explained by considering that acute flares induced by skin infiltration due to Staphylococcus aureus subsided with exposure to the acidic hot-spring water. Therefore, balneotherapy at Kusatsu can be useful for the treatment of refractory cases of atopic dermatitis.

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