Giant Cell Reparative Granuloma of the Temporal Bone: Neuroradiological and Immunohistochemical Findings. Case Report.
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- YOSHIMURA Junichi
- Department of Neurosurgery, Brain Research Institute, Niigata University
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- ONDA Kiyoshi
- Department of Neurosurgery, Brain Research Institute, Niigata University
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- TANAKA Ryuichi
- Department of Neurosurgery, Brain Research Institute, Niigata University
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- TAKAHASHI Hitoshi
- Department of Pathology, Brain Research Institute, Niigata University
書誌事項
- タイトル別名
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- —Case Report—
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A 38-year-old man presented with a giant cell reparative granuloma (GCRG) of the left temporal bone. Computed tomography showed a osteolytic middle cranial mass lesion. Magnetic resonance (MR) imaging showed the lesion as low intensity with heterogeneous enhancement by gadolinium on the T1-weighted images, and extremely low intensity on the T2-weighted images. Angiography showed the lesion as highly vascular and fed by branches of the left external carotid artery. After preoperative embolization, gross total removal of the tumor was performed. The postoperative course was uneventful and no evidence of recurrence has been found for more than 4 years. Histological examination revealed GCRG with multinucleated giant cells in the fibrous background, abundant collagen bundles, hemosiderin deposits, and trabeculae of reactive bone. Some of the mononuclear stromal cells and almost all of the giant cells were positive for CD68, suggesting histiocytic differentiation. These histological features reflect the marked decrease in signal intensity on T2-weighted MR images.<br>
収録刊行物
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- Neurologia medico-chirurgica
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Neurologia medico-chirurgica 42 (11), 510-515, 2002
一般社団法人 日本脳神経外科学会
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詳細情報 詳細情報について
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- CRID
- 1390001205049850496
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- NII論文ID
- 110002277033
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- NII書誌ID
- AN00358613
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- COI
- 1:STN:280:DC%2BD38jhtVWjsQ%3D%3D
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- ISSN
- 13498029
- 04708105
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- PubMed
- 12472217
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- 本文言語コード
- en
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- データソース種別
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- JaLC
- Crossref
- PubMed
- CiNii Articles
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- 使用不可