Drug-induced Hypotension SEP Test and Acetazolamide Test Using <SUP>133</SUP>Xe SPELT in Patients with Occlusive Carotid Disease
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- KURODA Satoshi
- Department of Neurosurgery, Hokkaido University School of Medicine
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- KAMIYAMA Hiroyasu
- Department of Neurosurgery, Hokkaido University School of Medicine
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- ABE Hiroshi
- Department of Neurosurgery, Hokkaido University School of Medicine
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- TAKIGAWA Shugo
- Department of Neurosurgery, Hokkaido University School of Medicine
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- MITSUMORI Kenji
- Hokkaido Neurosurgical Memorial Hospital
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- NOMURA Mikio
- Sapporo Azabu Neurosurgical Hospital
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- SAITOH Hisatoshi
- Sapporo Azabu Neurosurgical Hospital
書誌事項
- タイトル別名
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- —Selection of Candidates for Extracranial-intracranial Bypass—
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The correlation between the drug-induced hypotension somatosensory evoked potential (SEP) test and regional cerebral blood flow changes after acetazolamide administration was studied. Fourteen patients presenting with transient ischemic attack, reversible ischemic neurological deficits, or minor completed stroke were evaluated. All patients had no or only localized low-density areas on computed tomographic scans, and unilateral occlusion or severe stenosis of the internal carotid or middle cerebral artery on cerebral angiograms. The Diamox® asymmetry enhancement (DAE) was studied to detect reduced cerebral perfusion reserve in the affected hemispheres. The DAE was 7.9 ± 5.8% in seven patients positive in the SEP test, significantly higher than -1.5 ± 2.9% in patients negative in the SEP test. Postoperative SEP tests were negative in all five patients who underwent extracranialintracranial (EC-IC) bypass surgery, suggesting that the EC-IC bypass improved the cerebral perfusion reserve in the affected hemispheres. The DAE decreased significantly in four of these patients. This study disclosed a significant correlation between the drug-induced hypotension SEP test and DAE. These parameters are considered important for evaluating patients with hemodynamic compromise and/or suitable candidates for EC-IC bypass.
収録刊行物
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- Neurologia medico-chirurgica
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Neurologia medico-chirurgica 31 (1), 7-12, 1991
一般社団法人 日本脳神経外科学会
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詳細情報 詳細情報について
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- CRID
- 1390001205052057856
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- NII論文ID
- 110002278159
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- NII書誌ID
- AN00358613
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- DOI
- 10.2176/nmc.31.7
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- COI
- 1:STN:280:By6A3cvmtlA%3D
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- ISSN
- 13498029
- 04708105
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- PubMed
- 1712925
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- 本文言語コード
- en
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- データソース種別
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- JaLC
- Crossref
- PubMed
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可