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- KAWAKAMI Yasuto
- Department of Neurological Surgery, Kobe West Municipal Hospital
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- TANIMOTO Takaho
- Department of Neurological Surgery, Kobe West Municipal Hospital
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- SHIMAMURA Yutaka
- Department of Neurological Surgery, Kobe West Municipal Hospital
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Coagulation factors were studied in 30 fluids aspirated from 25 patients with chronic subdural hematoma. Compared with the normal range for plasma, the hematoma fluids demonstrated a marked reduction in factors II, V, VII, VIII, and X, moderate reduction of factors IX and XI, and slight reduction of XII. Factor VIII and IX inhibitors were not present or negligible. Activated protein C and antithrombin III were decreased and fibrinopeptide A was markedly increased. No case had a basic disorder causing these abnormal data spontaneously. The decrease in activated protein C possibly caused the marked reduction of factor VIII, therefore the intrinsic and extrinsic clotting pathways were affected differently. The results show excessive activation of coagulation, predominantly via the extrinsic clotting pathway in hematoma, suggesting its importance in the growth of chronic subdural hematoma.
収録刊行物
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- Neurologia medico-chirurgica
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Neurologia medico-chirurgica 31 (1), 32-36, 1991
一般社団法人 日本脳神経外科学会
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詳細情報 詳細情報について
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- CRID
- 1390001205052038400
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- NII論文ID
- 110002278163
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- NII書誌ID
- AN00358613
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- COI
- 1:STN:280:By6A3cvmt10%3D
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- ISSN
- 13498029
- 04708105
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- PubMed
- 1712920
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- 本文言語コード
- en
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- データソース種別
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- JaLC
- Crossref
- PubMed
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可