Effects of encephalo-duro-arterio-synangiosis on childhood moyamoya patients-swift disappearance of ischemic attacks and maintenance of mental capacity.

DOI Web Site PubMed 被引用文献11件
  • MATSUSHIMA Yoshiharu
    Department of Neurosurgery, Tokyo Medical and Dental University School of Medicine
  • AOYAGI Masaru
    Department of Neurosurgery, Tokyo Medical and Dental University School of Medicine
  • KOUMO Yoshihiko
    Department of Neurosurgery, Tokyo Medical and Dental University School of Medicine
  • TAKASATO Yoshio
    Department of Neurosurgery, Tokyo Medical and Dental University School of Medicine
  • YAMAGUCHI Takekane
    Department of Neurosurgery, Tokyo Medical and Dental University School of Medicine
  • MASAOKA Hiroyuki
    Department of Neurosurgery, Tokyo Medical and Dental University School of Medicine
  • SUZUKI Ryuta
    Department of Neurosurgery, Tokyo Medical and Dental University School of Medicine
  • OHNO Kikuo
    Department of Neurosurgery, Tokyo Medical and Dental University School of Medicine

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タイトル別名
  • Effects of Encephalo-duro-arterio-synangiosis on Childhood Moyamoya Patients
  • —Swift Disappearance of Ischemic Attacks and Maintenance of Mental Capacity—

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抄録

The effect of encephalo-duro-arterio-synangiosis (EDAS) upon chronic cerebrovascular ischemia in 65 pediatric moyamoya patients was evaluated by the postoperative interval before complete disappearance of ischemic attacks and changes in pre- and postoperative intelligence (IQ) or development quotients (DQ). The ischemic attacks disappeared after a mean period of 239 days, in three-fourths of patients within a year and in about one-fourth within the second year. This was very fast compared with the natural course of the disease. There was no significant difference in DQ/IQ before and after the operation. The mentally normal (IQ/DQ ≥ 86) population in the postoperative patients was greater than in the natural course of the disease, although fewer in the preoperative group. This shows that EDAS delayed or prevented the deterioration in mental capacity usually present but often overlooked in the natural course of pediatric moyamoya disease.

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