A Case of Severe Verapamil Overdose

• OE Hiroshi

  Department of Cardiology, Kita Osaka Hospital

• TANIURA Takehito

  Department of Cardiology, Kita Osaka Hospital

• OHGITANI Nobuhisa

  Department of Cardiology, Kita Osaka Hospital

抄録

We report here on a 73-year-old woman who ingested 3.6g(40mg×90 tablets)of verapamil in a suicide attempt. On arrival, the patient was awake and well oriented. Two and a half hours after ingestion, she lost consciousness, as her heart rate and blood pressure began to decrease. Cardiac monitoring showed atrioventricular dissociation. Although she suffered from extreme hypotension, an echocardiogram revealed that the wall motion of the heart was almost normal, and cardiac output measured with a Swan-Ganz catheter was well preserved. The plasma verapamil concentration in this patient was 1499 ng/ml 4h after ingestion. Hyperglycemia and hypokalemia, laboratory data revealed, continued for 18h after admission. The patient was successfully resuscitated with intravenous saline, dopamine, and norepinephrine. Besides reporting on this case, we also report on a treatment for severe verapamil overdose.

収録刊行物

• Japanese circulation journal

  Japanese circulation journal 62 (1), 72-76, 1997-12-20

  社団法人日本循環器学会

キーワード

• Verapamil
• Overdose
• Hypotension
• Treatment

詳細情報

• CRID: 1572824502057799168
• NII論文ID: 110002561093
• NII書誌ID: AA00690731
• ISSN: 00471828
• Web Site: https://search.jamas.or.jp/link/ui/1998109899
• 本文言語コード: en
• データソース種別:
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