Cholesterol and bile acid metabolism in hypertensive arteriolipidosis-prone rats (ALR).
書誌事項
- タイトル別名
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- Cholesterol and Bile Acid Metabolism in
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Bile flow and biliary bile acids were analyzed in arteriolipidosis-prone rats (ALR), the hypertensive model for lipidemic arterial lesions with reactive hypercholesterolemia and compared to those in spontaneously hypertensive rats (SHR) and normotensive Wistar-Kyoto rats (WKY). Bile flow and bile acid secretion decreased in the order of WKY, SHR and ALR. When labelled cholesterol was given intraperitoneally, the biliary radioactivity secretion was significantly slow in ALR in comparison with that in WKY. The decay of radioactive cholesterol in serum after the injection was also delayed in ALR. Our data suggest that the abnormality in bile flow, biliary bile acid secretion and/or cholesterol turnover to bile acids may be pathogenically related to reactive hypercholesterolemia noted in the ALR.
収録刊行物
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- JAPANESE CIRCULATION JOURNAL
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JAPANESE CIRCULATION JOURNAL 46 (2), 151-155, 1982
社団法人 日本循環器学会
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詳細情報
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- CRID
- 1390282681409357952
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- NII論文ID
- 130003546968
- 110002565528
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- NII書誌ID
- AA00690731
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- COI
- 1:CAS:528:DyaL38XhsVSlt7c%3D
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- ISSN
- 13474839
- 00471828
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- NDL書誌ID
- 2482084
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- PubMed
- 7057614
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- 本文言語コード
- en
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- データソース種別
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- JaLC
- NDL
- Crossref
- PubMed
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可