Activation - Recovery Intervals of 12-Lead Electro-cardiograms Before and After Catheter Ablation in Patients With Wolff-Parkinson-White Syndrome

  • Nonokawa Makoto
    Division of Cardiology, First Department of Internal Medicine, Nagoya University School of Medicine
  • Hirai Makoto
    Division of Cardiology, First Department of Internal Medicine, Nagoya University School of Medicine
  • Akahoshi Makoto
    Division of Cardiology, First Department of Internal Medicine, Nagoya University School of Medicine
  • Inden Yasuya
    Division of Cardiology, First Department of Internal Medicine, Nagoya University School of Medicine
  • Yoshida Yukihiko
    Division of Cardiology, Nagoya Daini Red Cross Hospital
  • Ito Teruo
    Division of Cardiology, Nagoya Daini Red Cross Hospital
  • Yokoyama Yumiko
    Division of Cardiology, First Department of Internal Medicine, Nagoya University School of Medicine
  • Sawada Takahisa
    Division of Cardiology, First Department of Internal Medicine, Nagoya University School of Medicine
  • Shimizu Atsuya
    Division of Cardiology, First Department of Internal Medicine, Nagoya University School of Medicine
  • Takada Yasunobu
    Division of Cardiology, First Department of Internal Medicine, Nagoya University School of Medicine
  • Iino Shigeo
    Division of Cardiology, First Department of Internal Medicine, Nagoya University School of Medicine
  • Kondo Takahisa
    Division of Cardiology, First Department of Internal Medicine, Nagoya University School of Medicine
  • Saito Hidehiko
    Division of Cardiology, First Department of Internal Medicine, Nagoya University School of Medicine

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Preexcitation in Wolff-Parkinson-White syndrome (WPW) has been reported to induce long-lasting changes in ventricular recovery properties. However, there has not been a report concerning changes in the activation - recovery interval (ARI) in 12-lead ECGs before and after catheter ablation (CA) in patients with WPW syndrome. The present study compared changes in ARIs from 12-lead ECGs with those from body surface unipolar leads before and after CA to examine whether ARIs from limb leads of 12-lead ECGs provide useful information on changes in recovery properties in addition to the ARIs from precordial leads. The study population consisted of 27 manifest WPW patients with a left- (n=18, group A) or right-sided accessory pathway (n=9, group B). ARIs in leads I, II, and III were strongly correlated with those in unipolar leads over the left lateral, left lower, and right lower chest, respectively. ARIs in leads aVR, aVL, and aVF showed a significant correlation with those in unipolar leads over the right upper, left upper, and lower anterior chest, respectively. These correlations were maintained before and after CA. Furthermore, in group A, ARIs in lead V1 tended to increase on day 7 post CA compared with before CA and on day 1. In group B, ARIs in lead III significantly decreased on day 7 compared with before CA and on day 1. These findings suggest that ARIs from the limb leads of 12-lead ECGs may represent those from unipolar leads of a particular area over the body surface, and that ARIs from 12-lead ECGs may provide useful quantitative information on changes in recovery properties before and after CA in patients with manifest WPW syndrome. (Jpn Circ J 2001; 65: 294 -299)

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