Declining Trend in the In-Hospital Case-Fatality Rate From Acute Myocardial Infarction in Miyagi Prefecture From 1980 to 1999.

  • Watanabe Jun
    Tohoku University Graduate School of Medicine, Department of Cardiovascular Medicine
  • Iwabuchi Kaoru
    Tohoku University Graduate School of Medicine, Department of Cardiovascular Medicine
  • Koseki Yoshito
    Tohoku University Graduate School of Medicine, Department of Cardiovascular Medicine
  • Fukuchi Mitsumasa
    Tohoku University Graduate School of Medicine, Department of Cardiovascular Medicine
  • Shinozaki Tsuyoshi
    Tohoku University Graduate School of Medicine, Department of Cardiovascular Medicine
  • Miura Masahito
    Tohoku University Graduate School of Medicine, Department of Cardiovascular Medicine
  • Komaru Tatsuya
    Tohoku University Graduate School of Medicine, Department of Cardiovascular Medicine
  • Kagaya Yutaka
    Tohoku University Graduate School of Medicine, Department of Cardiovascular Medicine
  • Shirato Kunio
    Tohoku University Graduate School of Medicine, Department of Cardiovascular Medicine
  • Kitaoka Shigenori
    Miyagi Study Group of Acute Myocardial Infarction (Miyagi-Ken Shinkin Kousoku Taisaku Kyogikai)
  • Ishide Nobumasa
    Miyagi Study Group of Acute Myocardial Infarction (Miyagi-Ken Shinkin Kousoku Taisaku Kyogikai)
  • Takishima Tamotsu
    Miyagi Study Group of Acute Myocardial Infarction (Miyagi-Ken Shinkin Kousoku Taisaku Kyogikai)

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The case-fatality rate from acute myocardial infarction (AMI) appears to have been declining in recent decades, so the present study reviewed the trend in in-hospital case-fatalities from AMI in Miyagi Prefecture, Japan, 1980-1999. The causes of death and the effects of gender and age on the trend were also analyzed. From the AMI registration database of the Miyagi Study Group for AMI, 12,961 cases of AMI were analyzed. The 30-day in-hospital case-fatality was calculated from the data for 1980-1999: data for causes of death were available for 1980-1997, and the data concerning primary percutaneous transluminal coronary angioplasty (PTCA) for AMI were available for 1997-1999. The in-hospital case-fatality rate declined from 17.0% in the early 80s to 7.3% in the late 90s (approximately 57% reduction). The in-hospital case-fatality rate was higher in female patients. Rhythm failure substantially decreased in the late 1980s. Pump failure is decreasing, but is still the biggest problem. The in-hospital case-fatality rate was significantly lower in patients received PTCA. The declining trend in the in-hospital case-fatality rate suggests the benefits of current therapeutic procedures, including primary PTCA, for AMI. Pump failure is an important target for further decreasing the trend. (Jpn Circ J 2001; 65: 941 - 946)

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