Effect of Reperfusion Therapy on Cardiac Rupture After Myocardial Infarction in Japanese

• Ikeda Nahoko

  Cardiovascular Division, First Department of Integrated Medicine, Omiya Medical Center, Jichi Medical School

• Yasu Takanori

  Cardiovascular Division, First Department of Integrated Medicine, Omiya Medical Center, Jichi Medical School

• Kubo Norifumi

  Cardiovascular Division, First Department of Integrated Medicine, Omiya Medical Center, Jichi Medical School

• Hirahara Taishi

  Cardiovascular Division, First Department of Integrated Medicine, Omiya Medical Center, Jichi Medical School

• Sugawara Yoshitaka

  Cardiovascular Division, First Department of Integrated Medicine, Omiya Medical Center, Jichi Medical School

• Kobayashi Nobuhiko

  Cardiovascular Division, First Department of Integrated Medicine, Omiya Medical Center, Jichi Medical School

• Hashimoto Shigemasa

  Cardiovascular Division, First Department of Integrated Medicine, Omiya Medical Center, Jichi Medical School

• Tsuruya Yoshio

  Cardiovascular Division, First Department of Integrated Medicine, Omiya Medical Center, Jichi Medical School

• Fujii Mikihisa

  Cardiovascular Division, First Department of Integrated Medicine, Omiya Medical Center, Jichi Medical School

• Saito Muneyasu

  Cardiovascular Division, First Department of Integrated Medicine, Omiya Medical Center, Jichi Medical School

抄録

Background Cardiac rupture after acute myocardial infarction (AMI) is unpredictable and almost always fatal, so the present study reviewed all the clinical characteristics of patients with cardiac rupture to determine if its occurrence can be predicted. Methods and Results The clinical characteristics of 1,296 consecutive AMI patients from January 1992 to February 2002 were retrospectively evaluated using multi-logistic analysis. Cardiac rupture occurred in 45 patients (3.5%), comprising left ventricular free wall rupture (n=23), ventricular septal perforation (n=20) and papillary muscle rupture (n=2). Early-phase rupture (within 72 h after AMI onset) was associated with anterior infarction. Of the 45 patients who experienced ruptures, 24 (53.3%) survived to discharge; 21 (46.6%) of the 45 ruptures occurred after admission. Successful reperfusion therapy was performed within 24 h for 840 patients. The incidence of rupture was significantly lower for reperfused patients than for non-reperfused patients (0.6% vs 3.5%, respectively; p<0.01). Peak C-reactive protein concentration was a reliable predictor of late-phase rupture (p=0.01), but not of early-phase rupture. Conclusions Reperfusion therapy appears to aid in the prevention of cardiac rupture, especially late-phase rupture. (Circ J 2004; 68: 422 - 426)<br>

収録刊行物

• Circulation Journal

  Circulation Journal 68 (5), 422-426, 2004

  一般社団法人 日本循環器学会

キーワード

• Cardiac rupture
• Myocardial infarction
• Reperfusion

詳細情報

• CRID: 1390282680078976512
• NII論文ID: 110002667552
• NII書誌ID: AA11591968
• DOI: 10.1253/circj.68.422
• ISSN: 13474820
• ISSN: 13469843
• ISSN: http://id.crossref.org/issn/13469843
• PubMed: 15118282
• Web Site: http://www.jstage.jst.go.jp/article/circj/68/5/68_5_422/_pdf
• Web Site: https://search.jamas.or.jp/link/ui/2006262452
• 本文言語コード: en
• データソース種別:
  • JaLC
  • Crossref
  • PubMed
  • CiNii Articles
• 抄録ライセンスフラグ: 使用不可