Effects of Spinach Extract on the Differentiation of the Human Promyelocytic Cell Line, HL-60.

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The effects of a non-dialyzable extract of spinach on the differentiation of HL-60 leukemia cell line were examined. The non-dialyzable extract of fresh and freeze-dried spinach induced the ability of nitroblue tetrazolium reduction and alpha-naphthyl butyrate esterase activity of HL-60 cells. These results suggest that non-dialyzable extract of spinach induces the differentiation of HL-60 cells into monocytes.

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