Differential Response of Obese Gene Expression from Fasting in Bovine Adipose Tissues.

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  • KIM Hyungha
    Department of Genetic Engineering, Chonnam National University
  • CHI Yountae
    Department of Genetic Engineering, Chonnam National University
  • CHUNG Kichul
    Department of Genetic Engineering, Chonnam National University
  • KIM Kwanghyun
    Department of Animal Resources, Biotechnology Research Institute, College of Agriculture, Chonnam National University
  • CHOI Yunjaie
    School of Agricultural Biotechnology, Seoul National University
  • BAIK Myunggi
    Department of Genetic Engineering, Chonnam National University

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  To understand the molecular mechanism for intramuscular fat deposition, the expression of the obese gene was examined in response to fasting. Food deprivation for 48 h induced a decrease in the level of obese mRNA in pooled adipose tissues (abdominal, perirenal, subcutaneous, intermuscular and intramuscular). The expression of obese mRNA was examined for individual adipose tissue from several fat depots. It was highly expressed in perirenal adipose tissue, but fasting did not affect its expression level in this tissue. Moderate levels were detected in subcutaneous and intermuscular adipose tissues, and a fasting-induced decrease in obese mRNA was apparent in these tissues. The expression level of the obese gene in intramuscular adipose tissue was very low and did not respond to fasting.<br>

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