Effects of Corticosterone on Connectin Content and Protein Breakdown in Rat Skeletal Muscle.

  • HAYASHI Kunioki
    Department of Biochemical Science and Technology, Faculty of Agriculture, Kagoshima University
  • TADA Osamu
    Department of Biochemical Science and Technology, Faculty of Agriculture, Kagoshima University
  • HIGUCHI Kouji
    Department of Biochemical Science and Technology, Faculty of Agriculture, Kagoshima University
  • OHTSUKA Akira
    Department of Biochemical Science and Technology, Faculty of Agriculture, Kagoshima University

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  We examined the effects of a glucocorticoid, corticosterone, on calpain activity, connectin content and protein breakdown in rat muscle. The results indicated that calpain activity was increased by corticosterone and thus breakdown of connectin was stimulated followed by increased breakdown of skeletal muscle protein.<br>

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