Effect of Medium-chain Triglycerides on the Postprandial Triglyceride Concentration in Healthy Men

  • KASAI Michio
    <i>Division of Healthcare Science Research Laboratory, Nisshin Oil Mills LTD.</i>
  • MAKI Hideaki
    <i>Division of Healthcare Science Research Laboratory, Nisshin Oil Mills LTD.</i>
  • NOSAKA Naohisa
    <i>Division of Healthcare Science Research Laboratory, Nisshin Oil Mills LTD.</i>
  • AOYAMA Toshiaki
    <i>Division of Healthcare Science Research Laboratory, Nisshin Oil Mills LTD.</i>
  • OOYAMA Katsuhiko
    <i>Division of Healthcare Science Research Laboratory, Nisshin Oil Mills LTD.</i>
  • UTO Harumi
    <i>Institute of Environmental Science for Human Life, Ochanomizu University</i>
  • OKAZAKI Mitsuko
    <i>Kagawa Nutrition University</i>
  • IGARASHI Osamu
    <i>Ibaraki Christian University</i>
  • KONDO Kazuo
    <i>Institute of Environmental Science for Human Life, Ochanomizu University</i>

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  • Effect of Medium-chain Triglycerides on the Postprandial Triglyceride Concentration in Healty Men

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Abstract

  This study compared the serum lipid concentrations after a single dose of medium-chain triglycerides (MCT) or long-chain triglycerides (LCT) between individuals grouped according to the body mass index (BMI). Twenty-five males participated as volunteers, the test diet containing 10 g of MCT or LCT. Blood samples were collected up to 6 h after the intake of a test diets. The LCT diet resulted in significantly greater increases in areas under the curves (AUCs) for serum and chylomicron triglyceride in the BMI≥23 kg/m2 group than those in the BMI<23 kg/m2 group. The magnitude of response after intake of the MCT diet by the BMI≥23 kg/m2 group was significantly lower than that after the LCT diet. These results suggest that, in subjects with BMI≥23 kg/m2, the intake of MCT is preferable to that of LCT for maintaining postprandial triglyceride at a low concentration.<br>

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