Chromosomal Circularization in<i>Streptomyces griseus</i>by Nonhomologous Recombination of Deletion Ends
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- INOUE Shoichi
- <i>Department of Molecular Biotechnology, Graduate School of Advanced Sciences of Matter, Hiroshima University</i>
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- HIGASHIYAMA Koji
- <i>Department of Molecular Biotechnology, Graduate School of Advanced Sciences of Matter, Hiroshima University</i>
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- UCHIDA Tetsuya
- <i>Department of Molecular Biotechnology, Graduate School of Advanced Sciences of Matter, Hiroshima University</i>
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- HIRATSU Keiichiro
- <i>Department of Molecular Biotechnology, Graduate School of Advanced Sciences of Matter, Hiroshima University</i>
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- KINASHI Haruyasu
- <i>Department of Molecular Biotechnology, Graduate School of Advanced Sciences of Matter, Hiroshima University</i>
書誌事項
- タイトル別名
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- Chromosomal Circularization in Streptomyces griseus by Nonhomologous Recombination of Deletion Ends
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抄録
Streptomyces linear chromosomes frequently cause deletions at both ends spontaneously or by various mutagenic treatments, and concomitantly display dynamic structural changes such as circularization and arm replacement. We have cloned and sequenced the fusion junctions of circularized chromosomes in two deletion mutants of Streptomyces griseus. No homology and a 1-bp overlap were found between the deletion ends of the mutant chromosomes. Taking this together with previous results, we concluded that chromosomal circularization in Streptomyces occurs by nonhomologous recombination between deletion ends.<br>
収録刊行物
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- Bioscience, Biotechnology, and Biochemistry
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Bioscience, Biotechnology, and Biochemistry 67 (5), 1101-1108, 2003
公益社団法人 日本農芸化学会
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詳細情報 詳細情報について
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- CRID
- 1390001206475773184
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- NII論文ID
- 110002694184
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- NII書誌ID
- AA10824164
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- COI
- 1:CAS:528:DC%2BD3sXktlygur8%3D
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- ISSN
- 13476947
- 09168451
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- NDL書誌ID
- 6545894
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- PubMed
- 12834288
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- 本文言語コード
- en
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- データソース種別
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- JaLC
- NDL
- Crossref
- PubMed
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可