Absorptive Activity of Calcium in the Isolated Cecal Epithelium Adaptively Increased by 2 Week's Feeding Difructose Anhydride III in Rats

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  • MINEO Hitoshi
    <i>Northern Advancement Center for Science and Technology</i> <i>Division of Applied Bioscience, Graduate School of Agriculture, Hokkaido University</i>
  • AMANO Midori
    <i>Northern Advancement Center for Science and Technology</i> <i>Department of Food Science and Human Nutrition, Faculty of Human Life Science, Fuji Women's University</i>
  • CHIJI Hideyuki
    <i>Department of Food Science and Human Nutrition, Faculty of Human Life Science, Fuji Women's University</i>
  • SHIGEMATSU Norihiro
    <i>Central Research Center, Fancl Corporation</i>
  • TOMITA Fusao
    <i>Division of Applied Bioscience, Graduate School of Agriculture, Hokkaido University</i>
  • HARA Hiroshi
    <i>Division of Applied Bioscience, Graduate School of Agriculture, Hokkaido University</i>

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  • Absorptive Activity of Calcium in the Isolated Cecal Epithelium Adaptively Increased by 2 Week's Feeding of Difructose Anhydride III in Rats

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  We compared net Ca absorption and Lucifer Yellow (LY), a paracellular passage dye, permeability in the epithelium isolated from the rat small intestine, cecum, and colon after feeding with control and difructose anhydride (DFA) III diets for 14 days using the Ussing chamber system. Feeding of DFA III increased net Ca transport and LY passage in the cecal but not in small intestinal or colonic epithelium. Ability of paracellular Ca passage via Tight-junction (TJ) in the cecum was changed adaptively by feeding of DFA III. Changes in microbial fermentation may affect the functional changes of Ca transport in cecal epithelium itself.<br>

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