A Case of Pulmonary Sarcoidosis with Advanced Cavitary Lesions Which Responded to Steroid Pulse Therapy

• Nagata Akira

  First Department of Internal Medicine, Nagoya City University Medical School

• Yamada Yasuo

  First Department of Internal Medicine, Nagoya City University Medical School

• Nakamura Atsushi

  First Department of Internal Medicine, Nagoya City University Medical School

• Asano Takayuki

  First Department of Internal Medicine, Nagoya City University Medical School

• Katoh Takasi

  First Department of Internal Medicine, Nagoya City University Medical School

• Imai Kengo

  First Department of Internal Medicine, Nagoya City University Medical School

• Itoh Makoto

  First Department of Internal Medicine, Nagoya City University Medical School

Bibliographic Information

Other Title

• ステロイドパルス療法が奏効した空洞病変を有したサルコイドーシスの 1 例

Abstract

A 27-year-old man with a past history of sarcoidosis-associated uveitis presented with a dry cough. He was admitted to our hospital for the evaluation of advanced lung fibrosis and cavitary lesions in the upper lung field on his chest X-ray film. The chest CT on admission showed multiple cavitary lesions with thick walls and nodular opacities in both upper lobes. Bronchoscopy on admission showed vascular network vessels at the carina and granular lesion in the right B5. Pulmonary sarcoidosis was diagnosed by bronchial biopsy. Three regimens of methylprednisolone (1g/day, i.v.) for three days at 7 day interval dramatically improved clinical symptom, lung function, lung fibrotic lesions on the chest X-ray film, and also bronchoscopic granular lesions, although chest CT scan revealed that cavitary lesions with thin walls remained. The steroid pulse therapy was followed by prednisolone (30mg/day, p.o.) and its dose was gradually decreased to 5mg/day. There has been no sign of reccurrence for 14 months since the first therapy.

Journal

• The Journal of the Japan Society for Respiratory Endoscopy

  The Journal of the Japan Society for Respiratory Endoscopy 21 (2), 113-117, 1999

  The Japan Society for Respiratory Endoscopy

Keywords

• Cavitary lesion
• Pulmonary sarcoidosis
• Steroid pulse therapy

Details

• CRID: 1390001204744993536
• NII Article ID: 110002820647
• NII Book ID: AN00357687
• DOI: 10.18907/jjsre.21.2_113
• ISSN: 21860149
• ISSN: 02872137
• Web Site: https://search.jamas.or.jp/link/ui/1999188093
• Text Lang: ja
• Data Source:
  • JaLC
  • CiNii Articles
• Abstract License Flag: Disallowed