高周波分光法を用いるD-グルコースの異性化反応の追跡  [in Japanese] High-frequency spectroscopic study on the isomerization of a D-glucose aqueous solution  [in Japanese]

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Author(s)

Abstract

糖はその分子内に多数のOH基を有する有機物であり, 水溶液中で変旋光を示す. D-グルコースでは, 水溶液中で1位のOH基の立体配置に基づくα,β異性化が起こるため, 糖分子周囲の水和構造にも変化が生じると考えられる. 高周波分光法は, 溶液構造変化あるいは分子どうしの会合状態変化を鋭敏に検出することが可能である. 今回, D-グルコースのα,β異性化反応過程を高周波分光法により追跡し, 1800MHz付近の共振ピークが反応時間によってその吸収強度に変化が生じることを見いだした. 吸収強度変化は, 異性化反応時間との間に直線関係が成立し, 比旋光度変化との間にもよい相関が得られた.

Saccharides have many hydroxyl groups in their molecular formulas and show mutarotation in aqueous solutions. Because of this, during the α,β isomerization of a D-glucose solution, a rearrangement of hydration occurs around the D-glucose molecules based on a stereochemical change of OH (1). High-frequency spectroscopy is an analytical method which is sensitive to the solution structures and/or a change of state of association between molecules. We applied the high-frequency method to the study of the α,β isomerization of D-glucose. The absorption intensity around 1800 MHz of high-frequency spectra was found to decrease with the progress of the isomerization reaction of D-glucose. The decrease of the intensity showed a linear relation with the reaction time. These results were found to agree with the rate of the reaction obtained from a rotation-angle measurement.

Journal

  • Bunseki kagaku

    Bunseki kagaku 51(9), 735-739, 2002-09-05

    The Japan Society for Analytical Chemistry

References:  13

Codes

  • NII Article ID (NAID)
    110002905127
  • NII NACSIS-CAT ID (NCID)
    AN00222633
  • Text Lang
    JPN
  • Article Type
    ART
  • ISSN
    05251931
  • NDL Article ID
    6300759
  • NDL Source Classification
    ZP4(科学技術--化学・化学工業--分析化学)
  • NDL Call No.
    Z17-9
  • Data Source
    CJP  NDL  NII-ELS  J-STAGE  NDL-Digital 
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