自己組織化単分子膜修飾電極を用いるドーパミンの選択的定量と共存タンパクの影響

• 陳 智棟

  江蘇工業学院化学工程系

• 長岡 勉

  大阪府立大学先端科学研究所

書誌事項

タイトル別名

• Selective determination of dopamine based on a self-assembled monolayer electrode with antifouling activity on protein adsorption
• ジコ ソシキカタンブンシ マク シュウショク デンキョク オ モチイル ドーパミン ノ センタクテキ テイリョウ ト キョウゾン タンパク ノ エイキョウ

抄録

A self-assembled monolayer consisting of 3,3'-thiodipropionic acid and n-decyl mercaptan formed on a gold electrode was studied for a sensitive and selective determination of dopamine. The experimental results show that the monolayer exhibits both excellent sensitivity and stability, even in the presence of ascorbic acid and protein. A detection limit of 5.0×10⁻⁶ M for dopamine was obtained in flow injection analysis by the optimizing experimental conditions, such as the solution pH, flow velocity of the carrier solution and the electrode potential. The current response of the modified electrode showed excellent stability in the presence of 0.2% albumin. Even with ascorbic acid in 10-fold excess, dopamine could be detected within an error of about 3%.<br>

収録刊行物

• 分析化学

  分析化学 53 (11), 1321-1324, 2004

  公益社団法人 日本分析化学会

キーワード

• self-assembly electrode
• amperometric flow-injection analysis
• dopamine
• ascorbic acid
• protein adsorption

詳細情報

• CRID: 1390282679332419712
• NII論文ID: 110002909986
• NII書誌ID: AN00222633
• DOI: 10.2116/bunsekikagaku.53.1321
• COI: 1:CAS:528:DC%2BD2cXhtVWjtbfM
• NDL書誌ID: 7149903
• ISSN: 05251931
• Web Site: http://id.ndl.go.jp/bib/7149903
• Web Site: https://ndlsearch.ndl.go.jp/books/R000000004-I7149903
• Web Site: http://www.jstage.jst.go.jp/article/bunsekikagaku/53/11/53_11_1321/_pdf
• Web Site: http://dl.ndl.go.jp/info:ndljp/pid/10895950
• 本文言語コード: ja
• データソース種別:
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