Cytocompatibility and Viscoelastic Properties of Phthalate Ester-free Tissue Conditioners

• HASHIMOTO Yoshiya

  Department of Biomaterials, Osaka Dental University

• NAKAMURA Masaaki

  Department of Biomaterials, Osaka Dental University

Abstract

We prepared prototype phthalate ester-free tissue conditioners (PFT) from a powder of poly (ethyl methacrylate) and a mixture of several liquids, including di-n-butyl sebacate, benzyl benzoate (BB), and ethanol. The estrogenic activities of the liquids in the PFT were measured by an E-screen assay. We also assessed the cytotoxicity of the prototype and commercial tissue conditioners against a living skin equivalent. Finally, the viscoelastic properties were determined by measuring the rubber hardness and initial flow, while the effect of the mixing liquid on the mechanical properties of a denture resin was assessed by three-point bending test. PFT did not show any estrogenic activity and displayed a low or a similar level of cytotoxicity as the conventional materials. The viscoelastic properties and the effect of the mixing liquid on mechanical properties were influenced by the quantity of BB present in the mixing liquid. The prototype is therefore a reasonable PFT candidate.

Journal

• Dental Materials Journal

  Dental Materials Journal 23 (3), 412-418, 2004

  The Japanese Society for Dental Materials and Devices

Keywords

• Cytocompatibility
• Phthalate ester-free
• Tissue conditioners

Details

• CRID: 1390282679692882688
• NII Article ID: 110002983572
• NII Book ID: AA10443149
• DOI: 10.4012/dmj.23.412
• COI: 1:CAS:528:DC%2BD2cXhtVOms7jO
• ISSN: 18811361
• ISSN: 02874547
• ISSN: http://id.crossref.org/issn/02874547
• PubMed: 15510874
• Web Site: https://www.jstage.jst.go.jp/article/dmj1982/23/3/23_3_412/_pdf
• Web Site: http://dl.ndl.go.jp/info:ndljp/pid/10744610
• Web Site: https://search.jamas.or.jp/link/ui/2005063548
• Text Lang: en
• Data Source:
  • JaLC
  • Crossref
  • PubMed
  • NDL-Digital
  • CiNii Articles
• Abstract License Flag: Disallowed