Comparison of Clinical Characteristics and Outcome of Young and Older Patients with Oral Squamous Cell Carcinoma.

DOI 被引用文献1件 参考文献8件
  • Ogura Ichiro
    Maxillofacial Surgery, Graduate School, Tokyo Medical and Dental University Department of Radiology, Nihon University School of Dentistry at Matsudo
  • Amagasa Teruo
    Maxillofacial Surgery, Graduate School, Tokyo Medical and Dental University
  • Ishii Junichi
    Maxillofacial Surgery, Graduate School, Tokyo Medical and Dental University
  • Iwaki Hiroshi
    Maxillofacial Surgery, Graduate School, Tokyo Medical and Dental University
  • Kurabayashi Tohru
    Oral and Maxillofacial Radiology, Graduate School, Tokyo Medical and Dental University
  • Sasaki Takehito
    Oral and Maxillofacial Radiology, Graduate School, Tokyo Medical and Dental University

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Oral squamous cell carcinoma (SCC) is relatively uncommon in patients less than 40 years of age. Of 411 patients with oral SCC treated, 27 patients (6.6%) were less than 40 years of age. These cases of young age were compared with those of older age concerning their clinical characteristics and outcome. The five-year overall survival rate was 92.6% for young and 68.8% for older patients, respectively (P = 0.027). Using logistic multivariate regression analysis, including age, gender, primary site, TN category and treatment modality, only TN category and treatment modality were significant and independent predictive variables for recurrence, but age was not (P < 0.05). It was concluded that better prognosis observed in young patients with oral SCC was significantly determined by their characteristics of TN category and treatment modality, but not by their age.

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