Hitological Study of Biocompatibility of New β Type Titanium Alloy (Ti-13Ta-29Nb-4.6Zr)
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- ITO Masamitsu
- Departments of Periodontology, School of Dentistry, Aichi-Gakuin University
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- BITO Boku
- Departments of Periodontology, School of Dentistry, Aichi-Gakuin University
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- YOSHINARI Nobuo
- Departments of Periodontology, School of Dentistry, Aichi-Gakuin University
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- MITANI Akio
- Departments of Periodontology, School of Dentistry, Aichi-Gakuin University
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- KAWASE Hitoshi
- Departments of Periodontology, School of Dentistry, Aichi-Gakuin University
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- MATSUOKA Masanori
- Departments of Periodontology, School of Dentistry, Aichi-Gakuin University
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- SUGIISHI Shin
- Departments of Periodontology, School of Dentistry, Aichi-Gakuin University
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- NOGUCHI Toshihide
- Departments of Periodontology, School of Dentistry, Aichi-Gakuin University
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- KAWAI Tatsushi
- Departments of Dental Material, School of Dentistry, Aichi-Gakuin University
Bibliographic Information
- Other Title
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- 新β型チタン合金(Ti-13Ta-29Nb-4.6Zr)の生体親和性に関する病理組織学的研究
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Abstract
The purpose of this study was to examine the biocompatibility of a newly developed β type titanium alloy (Ti-13Ta-29Nb-4.6Zr). Ti-13Ta-29Nb-4.6Zr, Ti-6Al-4V, Ti, Ni and Cu were implanted in subcutaneous pouches in the backs of ddy mice, and sham operations were performed on controls. Proinflammatory cytokines (IL-1 α, β, IL-6 and IL-1 ra) were detected in the tissues around the alloy by immunohistochemical methods. The results were as follows : the levels of expression of every proinflammatory cytokine in mice with Ti-13Ta-29Nb-4.6Zr implants were lower than in the Cu and Ni groups. However, the level of IL-1 β exoression induced by the new alloy was higher than in the Ti and sham groups, and a higher level of IL-6 expression than sham in the group was detected at 10 days. We concluded that Ti-13Ta-29Nb-4.6Zr may have equivalent biocompatibility to the existing Ti alloy However, our findings is suggested that the differences in the elements included in the materials may affect the host response.
Journal
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- The Journal of the Japanese Society for Dental Materials and Devices
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The Journal of the Japanese Society for Dental Materials and Devices 23 (1), 21-28, 2004
The Japanese Society for Dental Materials and Devices
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Keywords
Details 詳細情報について
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- CRID
- 1390282679187600768
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- NII Article ID
- 110002987453
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- NII Book ID
- AN00127279
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- ISSN
- 21884188
- 02865858
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- Text Lang
- ja
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- Data Source
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- JaLC
- CiNii Articles
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- Abstract License Flag
- Disallowed