虚弱歯槽骨に対する高カルシウム食・カルシトニンの併用療法に関する実験的研究 [in Japanese] An Experimental Study on a Combined Treatment Method of a High-calcium Diet and Calcitonin on Alveolar Bone Debility [in Japanese]
-
- 小野 清一郎 Ono Seiichiro
- 九州歯科大学大学院歯学研究科 Department of Pediatric Dentistry Kyushu Dental College
Access this Article
Search this Article
Author(s)
-
- 小野 清一郎 Ono Seiichiro
- 九州歯科大学大学院歯学研究科 Department of Pediatric Dentistry Kyushu Dental College
Abstract
Three-week-old male Wistar rats were maintained on a non-calcium diet or a low-calcium diet and bone debility was induced in them. Then the rats were given a high-calcium diet and eel calcitonin (ECT), and the effect on the alveolar bone was investigated. The results were as follows : 1. Analysis of radiological bone shadow density Al equivalence of the bone shadow density decreased in the order of the control group, the low-calcium diet, high-calcium diet and ECT group, the low-calcium diet and standard diet group, the non-calcium diet, high-calcium diet and ECT group. 2. Characteristic and quantitative analyses In every group, the characteristic X-ray image showed higher density Ca than P in any individual trabeculae. 3. Light microscopic findings As compared with the control group, higher bone absorption and higher decrease in bone quantity were observed in the non-calcium diet, high-calcium diet and ECT group and the low-calcium diet and standard diet group. In the low-calcium diet, high-calcium diet and ECT group, bone construction was accelerated highest next to the control group. 4. Scanning electron microscopic findings As compared with the control group, wider expansion of bone marrow and more extensive bone absorption findings were observed in the non-calcium diet, high-calcium diet and ECT group and the low-calcium diet and standard diet group. The low-calcium diet, high-calcium diet and ECT group showed morphologically similar findings to those of the control group. On the basis of the foregoing results, a combined treatment method of a high-calcium diet and calcitonin for alveolar bone debility has proved to accelerate remodeling in calcification of bone and bone construction.
Journal
-
- The Journal of the Kyushu Dental Society
-
The Journal of the Kyushu Dental Society 49(1), 70-90, 1995
KYUSHU DENTAL SOCIETY
References: 40
-
1
- カルシウム不足の成長期顎骨に対する生理活性物質の応用に関する透過型電顕的研究-とくに下顎頭の変化-
-
木村光孝
平成2年度歯科大学研究助成金研究成果報告書, 1991
Cited by (1)
-
2
- ビタミンDの成長期下顎頭に及ぼす影響に関する実験的研究
-
大倉秀一郎
九州歯会誌 44, 1-38, 1990
Cited by (1)
-
3
- Differential response in alveolar bone osteoclasts residing at two different bone sites
-
LIU C. C.
Calcif. Tissue Int. 36, 182-188, 1984
Cited by (1)
-
4
- Osteoporosis following calcium deficiency in rats
-
SALOMON C. D.
Calcif. Tissue Res. 8, 320-333, 1972
Cited by (1)
-
5
- Accumulation of mast cells in endosteum of bone of calcium-deficient rats
-
URIST M. R.
A. M. A. Arch. Pathol. 63, 239-251, 1957
Cited by (1)
-
6
- Mechanisms of bone resorption in calcium-deficient rats
-
SISSONS H. A.
Calcif. Tissue Int. 36, 711-721, 1984
Cited by (1)
-
7
- Alveolar bone resorption after calcium deficiency in rats
-
OKUDOH M.
Bull. Tokyo Med. Dent. Univ. 20, 131-144, 1973
Cited by (1)
-
8
- Effect of dietary calcium levels on production and reversal of experimental osteoporosis in cats
-
JOWSEY J.
Proc. Soc. Exp. Biol. Med. 116, 437-441, 1964
Cited by (1)
-
9
- Postmenopausal osteoporosis
-
ALBRIGHT F.
Trans. A. Amer. Phys. 55, 298-305, 1940
Cited by (1)
-
10
- 骨粗鬆症の臨床像
-
真田孝三
慈恵医大誌 80, 617-635, 1966
Cited by (1)
-
11
- 実験的骨粗鬆症に対する食餌療法に関する研究-特に歯槽骨について-
-
住本和孝
小児歯誌 23, 271-272, 1985
Ichushi Web Cited by (1)
-
12
- カルシウムの成長期顎骨に及ぼす影響に関するX線学的検索
-
木村光孝
小児歯誌 25, 521-530, 1987
Ichushi Web Cited by (8)
-
13
- 虚弱骨に対する食餌の影響に関する実験的研究-とくに下顎骨について-
-
木村光孝
小児歯誌 28, 949-955, 1990
Ichushi Web Cited by (6)
-
14
- 低カルシウム食飼育ラットにおける下顎頭軟骨の組織学的研究
-
松本文博
四国歯誌 3, 161-177, 1989
Ichushi Web Cited by (4)
-
15
- 低カルシウム食飼育ラットの臼歯部歯槽骨吸収の進行に関する研究
-
OHYA K.
口病誌 59, 585-593, 1992
Ichushi Web Cited by (8)
-
16
- Structure of rats and mice fed a low calcium diet
-
ORNOY A.
Calcif. Tissue Res. 15, 71-76, 1974
DOI Cited by (4)
-
17
- 血清カルシウム濃度の調節系
-
松本俊夫
Medicina 25, 1482-1484, 1988
Ichushi Web Cited by (1)
-
18
- An Experimental Study on the Mandible at Growth Stage and Calcium Intake : Change in the Mandibular Condyle in Particular [in Japanese]
-
Chen I Kon
The Journal of the Kyushu Dental Society 43(5), 710-745, 1989
J-STAGE Ichushi Web Cited by (14)
-
19
- A Study on the Effect of a Calcium-enriched Diet on Experimental Osteoporosis of Mandible at Growth Stage : Change in the Alveolar Bone in Particular [in Japanese]
-
Kimura Mitsutaka , Nishida Ikuko , Maki Kenshi , Yokomoto Mitsuru , Soga Humio , Ozaki Akitoshi , Huruya Mitsuaki , Takahashi Hirotake
The Journal of the Kyushu Dental Society 43(5), 778-801, 1989
J-STAGE Ichushi Web Cited by (7)
-
20
- A Radiological and Histopathological Study of Effects of Calcium on Experimental Osteoporosis : Especially Changes in the Alveolar Bone in Maturation Anaphase [in Japanese]
-
Kimoto Tsunehiro
The Journal of the Kyushu Dental Society 44(3), 556-581, 1990
J-STAGE Ichushi Web Cited by (9)
-
21
- Radiological, and Light and Scanning Electron Microscopic Study on the Effect of High-calcium Food on Bone Debility : Change in the Alveolar Bone [in Japanese]
-
Umezu Tetsuo
The Journal of the Kyushu Dental Society 45(6), 629-652, 1991
J-STAGE Ichushi Web Cited by (34)
-
22
- A Histopathological and Micromorphological Study on Calcium Treatment for Debilitated Mandibles : Especially Formation of Bone Matrix [in Japanese]
-
Nakagawara Tetsuro
The Journal of the Kyushu Dental Society 46(6), 764-781, 1992
J-STAGE Ichushi Web Cited by (19)
-
23
- An Experimental Study of Effect of Calcitonin on Jaw Bones at Growth Stage : Especially Changes in the Mandibular Condyle [in Japanese]
-
Hashimoto Toshiaki
The Journal of the Kyushu Dental Society 41(5), 886-915, 1987
J-STAGE Ichushi Web Cited by (4)
-
24
- A Study on the Effect of Calcitonin on Experimental Osteoporosis : Especially change in the alveolar bone [in Japanese]
-
Ajisaka Ichiro
The Journal of the Kyushu Dental Society 42(5), 523-558, 1988
J-STAGE Ichushi Web Cited by (14)
-
25
- An Experimental Study on the Effect of Calcitonin on the Jaw Bone in the Growth Stage : Especially change in the alveolar bone [in Japanese]
-
Shinjou Keiwa
The Journal of the Kyushu Dental Society 42(5), 648-688, 1988
J-STAGE Ichushi Web Cited by (7)
-
26
- A Study of Effect of Active Type Vitamin D_3 on Experimental Osteoporosis in the jaw Bones at Growth Stage : Especially changes in the alveolar bone [in Japanese]
-
Inoue Hideto
The Journal of the Kyushu Dental Society 42(6), 918-948, 1988
J-STAGE Ichushi Web Cited by (10)
-
27
- A Radiological, Light and Electron Microscope Study of the Effect of Active Type Vitamin D_3 on Experimental Osteoporosis : Especially Changes on the Mandibular Condyle at Growth Stage [in Japanese]
-
Iwanaga Norito
The Journal of the Kyushu Dental Society 43(1), 226-262, 1989
J-STAGE Ichushi Web Cited by (17)
-
28
- Radiological and Light and Electron Microscopic Studies of the Effect of a Physiologic Active Substance on Bone Debility : Especially Changes in the Mandibular Condyle [in Japanese]
-
Takano Osamu
The Journal of the Kyushu Dental Society 44(6), 890-919, 1990
J-STAGE Ichushi Web Cited by (9)
-
29
- An Experimental Study on a Combined Therapy of Calcium-containing Food and Active Type Vitamin D_3 for Bone Debility : Changes in the Alveolar Bone in Particular [in Japanese]
-
Kaku Hiroshi
The Journal of the Kyushu Dental Society 46(3), 462-481, 1992
J-STAGE Ichushi Web Cited by (14)
-
30
- Radiological Light and Electron Microscopic Study on Combined Therapy of Calcium and Physiologic Active Substance for Bone Debility : Especially Changes in the Mandibular Condyle [in Japanese]
-
Kinjou Takashi
The Journal of the Kyushu Dental Society 45(1), 143-174, 1991
J-STAGE Ichushi Web Cited by (11)
-
31
- An Experimental Study on the Treatment Method Combined with Physiologically Active Substance for Bone Debility : Especially Changes in the Alveolar Bone [in Japanese]
-
Uchino Kouichi
The Journal of the Kyushu Dental Society 45(4), 425-445, 1991
J-STAGE Ichushi Web Cited by (4)
-
32
- A Light and Electron Microscopic Study on the Combined Treatment Method of Calcitonin and Active Type Vitamin D_3 for Bone Debility : Changes in the Mandibular Condyle [in Japanese]
-
Inagawa Yujo
The Journal of the Kyushu Dental Society 46(1), 140-175, 1992
J-STAGE Ichushi Web Cited by (21)
-
33
- A Physiologic Active Substance Combined Therapy for Calcium-deficient Mandibular Condyles at Growth Stage [in Japanese]
-
Kimura Mitsutaka , Maki Kenshi , Inagawa Yujo , Watanabe Hiroshi , Wakasugi Junjiro , Soga Tomio , Yokomoto Mitsuru , Yanome Shizuteru , Braham Raymond L.
The Japanese Journal of Pediatric Dentistry 30(1), 69-79, 1992
J-STAGE Ichushi Web Cited by (1)
-
34
- A Study of Experimental Osteoporosis of the Jaw Bones at Growth Stage : especially of the alveolar bone [in Japanese]
-
Ishii Kimio
The Journal of the Kyushu Dental Society 40(3), 530-554, 1986
J-STAGE Ichushi Web Cited by (34)
-
35
- Radiological, Light Microscopic, and Electron Microscopic Studies of the Growth of the Jaw Bones : Changes in the Mandibular Condyle to Food Hardness [in Japanese]
-
Nakazono Shiho
The Journal of the Kyushu Dental Society 45(1), 1-23, 1991
J-STAGE Ichushi Web Cited by (9)
-
36
- Radiological, Light Microscopic, and Electron Microscopic Study on the Growth of the Jaw Bones : Changes in the Alveolar Bone due to Food Hardness [in Japanese]
-
Shuto Yoji
The Journal of the Kyushu Dental Society 46(4), 574-595, 1992
J-STAGE Ichushi Web Cited by (12)
-
37
- A Light and Scanning Electron Microscopic Study on a Combined Treatment Method of Calcium and Calcitonin for Debilitated Mandibles [in Japanese]
-
Sakamoto Yoshiko
The Journal of the Kyushu Dental Society 48(1), 6-28, 1994
J-STAGE Ichushi Web Cited by (6)
-
38
- A Study on Experimental Osteoporosis of the Mandible at Growing Stage : Especially on Change in Mandibular Condyle [in Japanese]
-
Nakao Toshio
The Journal of the Kyushu Dental Society 41(1), 46-67, 1987
J-STAGE Ichushi Web Cited by (22)
-
39
- A Study of Effect of Diet on Experimental Osteoporosis : Especially Change in the Mandibular Condyle [in Japanese]
-
Shinozaki Eiichi
The Journal of the Kyushu Dental Society 41(1), 102-121, 1987
J-STAGE Ichushi Web Cited by (15)
-
40
- Change in Values of Blood Components with Increasing Age in Rats [in Japanese]
-
Kimura Mitsutaka , Nishida Ikuko , Ozaki Akitoshi , Imamura Takako , Ota Kazuko , Murata Machiko
The Japanese Journal of Pediatric Dentistry 30(5), 1037-1047, 1992
J-STAGE Ichushi Web Cited by (16)
Cited by: 7
-
1
- A Radiological, Light Microscopic and Ultramicromorphological Study of Effect of Hyperprotein Meal on the Mandible at the Growth Stage : Formation of Bone Matrix [in Japanese]
-
Takaesu Noboru
The Journal of the Kyushu Dental Society 50(1), 39-58, 1996
J-STAGE Ichushi Web References (51) Cited by (2)
-
2
- An Experimental Study on Metatrophic Therapy in Juvenile Bone Debility : On Diaphyseal Cortex of Tibia [in Japanese]
-
Ozaki Akitoshi
The Journal of the Kyushu Dental Society 51(4), 441-461, 1997
J-STAGE Ichushi Web References (41) Cited by (11)
-
3
- Radiographic, Microscopic and Ultrastructural Study on Dietary Treatment of Mandibular Bone Loss at Growth Stage : Formation of Bone Matrix [in Japanese]
-
Saito Akira
The Journal of the Kyushu Dental Society 52(1), 1-32, 1998
J-STAGE Ichushi Web References (21) Cited by (1)
-
4
- Ultrastructural and Enzyme Histochemical Study on Dietary Treatment of Bone Debility in Growing Rats : On Formation of Bone Matrix [in Japanese]
-
Kanazawa Kazutaka
The Journal of the Kyushu Dental Society 52(1), 63-79, 1998
J-STAGE Ichushi Web References (48) Cited by (6)
-
5
- Densitometric and Histopathological Study of Dietary Treatment Effect on Bone Loss of Diaphysial Cortex of Tibita in Aged Rats : on Formation of Bone Matrix [in Japanese]
-
Fukui Masahiko
The Journal of the Kyushu Dental Society 52(1), 90-108, 1998
J-STAGE Ichushi Web References (46) Cited by (1)
-
6
- Densitometric and Histopathologic Study on Dietary Treatment on Bone Loss of Cortical Bone of Tibial Diaphysis in Growing Rat [in Japanese]
-
Kutsuna Hiromasa
The Journal of the Kyushu Dental Society 52(5), 533-556, 1998
J-STAGE Ichushi Web References (34)
-
7
- Effects of Unical^[○!R] Diet on the Development of the Mandibular Condyle Cartilage at the Growth Stage [in Japanese]
-
Morimoto Akiko
The Journal of the Kyushu Dental Society 54(1), 1-19, 2000
J-STAGE Ichushi Web References (60) Cited by (2)