胸郭内原発悪性線維性組織球腫の4例

書誌事項

タイトル別名
  • Malignant Fibrous Histiocytoma in the Thoracic Cage-Report of 4 Cases.

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抄録

Four cases of malignant fibrous histiocytoma (MFH) in the thoracic cage (1 originating in the lung, 2 in the mediastinum, 1 in the chest wall) were reported. Three cases were men and one was a woman, and the average age was 65 years. All four cases had inflammatory reactions. Two cases in which serum ferritin was measured, revealed high levels accompanying tumor enlargement. Ferritin was detected by immunohistochemical staining in the cytoplasm of a few tumor cells as well as reactive histiocytes proliferating in the tumor or surrounding inflammatory sites. These results demonstrated the production of ferritin from the tumor and suggested that the serum ferritin level may be a useful marker for tumor growth of MFH. This tumor revealed extremely rapid growth and MFH could not be diagnosed preoperatively. Although two cases were resected, both died within 7 months.<BR>The importance of making an early and correct pathological diagnosis by open lungbiopsy, followed by multimodal treatment was emphasized.

収録刊行物

  • 肺癌

    肺癌 37 (1), 75-82, 1997

    特定非営利活動法人 日本肺癌学会

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