特異な組織反応を示した胸腺セミノーマの2例  [in Japanese] Two Cases of Thymic Seminomas Showing Unusual Histological Reactions  [in Japanese]

Access this Article

Search this Article

Author(s)

    • 田中康一 Tanaka Koichi
    • 大分医科大学第2外科 The Second Department of Surgery Division of Pathology, Laboratory Center, Oita Medical University
    • 近間 英樹 Chikama Hideki
    • 大分医科大学第2外科 The Second Department of Surgery Division of Pathology, Laboratory Center, Oita Medical University
    • 岡田 秀司 Okada Shuji
    • 大分医科大学第2外科 The Second Department of Surgery Division of Pathology, Laboratory Center, Oita Medical University
    • 葉玉 哲生 Hadama Tetsuo
    • 大分医科大学第2外科 The Second Department of Surgery Division of Pathology, Laboratory Center, Oita Medical University
    • 内田 雄三 Uchida Yuzo
    • 大分医科大学第2外科 The Second Department of Surgery Division of Pathology, Laboratory Center, Oita Medical University
    • 横山 繁生 Yokoyama Shigeo
    • 大分医科大学中央検査部病理 The Second Department of Surgery Division of Pathology, Laboratory Center, Oita Medical University

Abstract

生体側の著明な二次反応の為に本来の腫瘍像が不明瞭となった胸腺セミノーマの2例を経験したので報告する.症例1は35才男性.検診で縦隔腫瘍が疑われ入院となった.胸部CTで前縦隔に嚢腫を認め胸腺全摘術を施行した.腫瘍は胸腺から発生した単胞性嚢腫で, 組織像はラングハンス型巨細胞を混じた多数の類上皮性肉芽腫が主体を占めていたが, それに接して明るい胞体を有するセミノーマ胞巣が認められた.症例2は27才男性.顔面浮腫を主訴とし, 某病院より前縦隔の巨大腫瘍と診断され, 手術目的で当院に紹介入院となった.しかし, 入院時すでに顔面浮腫はなく, 胸部X線写真では腫瘍は著明に退縮していた.この間, 全く投薬は受けていない.結局は完全退縮には至らず手術を施行した.腫瘍は胸腺から発生した充実性腫瘍で胸腺と共に摘出した.組織像は線維性組織が大部分を占めていたが, 僅かにセミノーマの胞巣が島状に認められた.######The authors presented two cases of unusual thymic seminomas in which secondary host reactions were so prominent as to obscure the underlying tumors. Case 1 was a 35-year-old man, whose chest roentgenograms showed an anterior mediastinal mass. At surgery, the intrathymic solitary cystic mass was removed. The histological appearance of the cystic wall was dominated by extensive sarcoid-like granulomatous inflammation. Among them, small clusters with seminomatous features were scattered. Case 2 was a 27-year-old man, transferred to our hospital with a complaint of facial edema and a diagnosis of giant anterior mediastinal tumor. Soon after admission, the size of the tumor decreased remarkably in spite of receiving no particular treatment. Eventually, surgical operation was performed, and intrathymic solid tumor was removed. The histological appearance of the tumor was dominated by dense fibrous scar tissue, but small foci of seminomatous appearance were present.

The authors presented two cases of unusual thymic seminomas in which secondary host reactions were so prominent as to obscure the underlying tumors. Case 1 was a 35-year-old man, whose chest roentgenograms showed an anterior mediastinal mass. At surgery, the intrathymic solitary cystic mass was removed. The histological appearance of the cystic wall was dominated by extensive sarcoid-like granulomatous inflammation. Among them, small clusters with seminomatous features were scattered. Case 2 was a 27-year-old man, transferred to our hospital with a complaint of facial edema and a diagnosis of giant anterior mediastinal tumor. Soon after admission, the size of the tumor decreased remarkably in spite of receiving no particular treatment. Eventually, surgical operation was performed, and intrathymic solid tumor was removed. The histological appearance of the tumor was dominated by dense fibrous scar tissue, but small foci of seminomatous appearance were present.

Journal

  • Japanese Journal of Lung Cancer

    Japanese Journal of Lung Cancer (32(7)), 1065-1070, 1992-12

    The Japan Lung Cancer Society

Cited by:  1

Codes

  • NII Article ID (NAID)
    110003124813
  • NII NACSIS-CAT ID (NCID)
    AN00203978
  • Text Lang
    JPN
  • Article Type
    Journal Article
  • ISSN
    0386-9628
  • Data Source
    CJPref  NII-ELS  IR 
Page Top