A Case of Pulmonary Epithelioid Hemangioendothelioma-Review of the Literature-.
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- Sakurai Hiroyuki
- Division of Thoracic Surgery, National Cancer Center Hospital
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- Suzuki Kenji
- Division of Thoracic Surgery, National Cancer Center Hospital
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- Watanabe Shunichi
- Division of Thoracic Surgery, National Cancer Center Hospital
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- Asamura Hisao
- Division of Thoracic Surgery, National Cancer Center Hospital
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- Tsuchiya Ryosuke
- Division of Thoracic Surgery, National Cancer Center Hospital
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- Maeshima Arahumi
- Division of Pathology, National Cancer Center Research Institute
Bibliographic Information
- Other Title
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- 肺類上皮血管内皮腫の1例―文献的考察を加えて―
- Review of the Literature
- 文献的考察を加えて
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Abstract
Background. Pulmonary epithelioid hemangioendothelioma (PEH) is a rare pulmonary neoplasm, which was formerly known as intravascular bronchioloalveolar tumor, IVBAT. We report a case of PEH, with multiple small nodules throughout both lung fields, and review the published reports. Case. A 63-year-old woman whose chief complaint was back pain was found to have multiple small nodules in both lungs on chest radiograph, and was referred to our hospital. Clinical examination and routine laboratory tests were within normal limits. Tumor markers were not elevated. Diagnostic open lung biopsy was performed. Histologically, the center of the nodule was occupied by a hyalinized matrix and the periphery of the nodules showed intraalveolar or polypoid proliferation of the tumor cells. Immunohistologic staining showed that tumor cells were positive for endothelial markers, CD31, CD34 and Factor VIII-related antigen. These findings were consistent with a diagnosis of PEH. Conclusion. The reported clinical course of PEH was usually relatively slow but sometimes rapid. We have no effective therapeutic regimens for PEH. The patient remains asymptomatic about 1 year 5 months after the diagnosis without treatment. We will carefully follow up this case.
Journal
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- Haigan
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Haigan 43 (2), 143-147, 2003
The Japan Lung Cancer Society
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Keywords
Details 詳細情報について
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- CRID
- 1390001204677598336
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- NII Article ID
- 130003920487
- 110003138148
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- NII Book ID
- AN00203978
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- ISSN
- 13489992
- 03869628
- http://id.crossref.org/issn/03869628
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- Text Lang
- ja
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- Data Source
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- JaLC
- Crossref
- CiNii Articles
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- Abstract License Flag
- Disallowed