約10年の臨床経過を有する粘液産生肺腺癌の1例  [in Japanese] A Case of Mucus-producing Adenocarcinoma of the Lung with a 10-year Clinical History  [in Japanese]

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Author(s)

    • 増本英男 Mashimoto Hideo
    • 佐世保市立総合病院内科 Department of Internal Medicine and Department of Surgery, Sasebo General City Hospital
    • 須山 尚史 Suyama Naohumi
    • 佐世保市立総合病院内科 Department of Internal Medicine and Department of Surgery, Sasebo General City Hospital
    • 荒木 潤 Araki Jun
    • 佐世保市立総合病院内科 Department of Internal Medicine and Department of Surgery, Sasebo General City Hospital
    • 浅井 貞宏 Asai Sadahiro
    • 佐世保市立総合病院内科 Department of Internal Medicine and Department of Surgery, Sasebo General City Hospital
    • 南 寛行 Minami Hiroyuki
    • 佐世保市立総合病院外科 Department of Internal Medicine and Department of Surgery, Sasebo General City Hospital

Abstract

患者は63歳,男性.約10年前より肺結核腫として観察されていた陰影が急速に増大してきたため入院となった.右上葉S^2を中心とする巨大な腫瘤で,右肺全摘出術が施行された.腫瘍は卵巣などにみられる嚢胞腺癌に類似した形態をとっていた.この興味ある腫瘍の組織発生に関しては,気管支腺よりも気管支表面上皮の杯細胞由来が示唆された.A 63-year-old man was admitted to our hospital because a pulmonary mass with a 10-year history had enlarged rapidly in recent years. Chest X-ray film on admission showed a large mass shadow in the right upper lobe. Bronchofiberscopy revealed a polypoid tumor with a smooth surface completely occluding right B^2. Right pneumonectomy was carried out as the histological findings of the biopsied specimen strongly suggested mucus-producing adenocarcinoma. Macroscopically, this well-circumscribed tumor contained abundant mucus. Microscopically, mucus-filled cyst walls consisted of mucus-secreting columnar cells. The pathological findings of the tumor resembled the mucinous cystadenocarcinoma originating in the ovary. Ultrastructure of the tumor showed a basal body in the cytoplasm. The tumor cells were weakly positive for lysozyme and negative for lactoferrin. These facts suggested that this tumor was derived from goblet cells rather than the bronchial gland.

A 63-year-old man was admitted to our hospital because a pulmonary mass with a 10-year history had enlarged rapidly in recent years. Chest X-ray film on admission showed a large mass shadow in the right upper lobe. Bronchofiberscopy revealed a polypoid tumor with a smooth surface completely occluding right B^2. Right pneumonectomy was carried out as the histological findings of the biopsied specimen strongly suggested mucus-producing adenocarcinoma. Macroscopically, this well-circumscribed tumor contained abundant mucus. Microscopically, mucus-filled cyst walls consisted of mucus-secreting columnar cells. The pathological findings of the tumor resembled the mucinous cystadenocarcinoma originating in the ovary. Ultrastructure of the tumor showed a basal body in the cytoplasm. The tumor cells were weakly positive for lysozyme and negative for lactoferrin. These facts suggested that this tumor was derived from goblet cells rather than the bronchial gland.

Journal

  • Japanese Journal of Lung Cancer

    Japanese Journal of Lung Cancer 31(2), 247-252, 1991-04-20

    The Japan Lung Cancer Society

Cited by:  18

Codes

  • NII Article ID (NAID)
    110003142623
  • NII NACSIS-CAT ID (NCID)
    AN00203978
  • Text Lang
    JPN
  • Article Type
    Journal Article
  • ISSN
    03869628
  • Data Source
    CJPref  NII-ELS  IR 
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