Evidence for Degeneration of Monoaminergic Fibers in the Spinal Cord of Zitter Mutant Rats.
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- Okuda Keiko
- Department of Anesthesiology, Dokkyo University School of Medicine
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- Saitoh Yuuki
- Department of Anesthesiology, Dokkyo University School of Medicine
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- Kitajima Toshimitsu
- Department of Anesthesiology, Dokkyo University School of Medicine
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- Yamaoka Sadao
- Department of Physiology, Dokkyo University School of Medicine
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- Ueda Shuichi
- Department of Histology and Neurobiology, Dokkyo University School of Medicine
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A distribution of abnormal catecholaminergic and serotonergic fibers was in the spinal cord of 12-month-old zitter mutant rats which are characterized by abnormal metabolism of superoxides studied using antisera for tyrosine hydroxylase (TH) and serotonin. Similar to our previous report [13], abnormal serotonergic fibers characterized by swollen varicosites were observed mainly in the anterior and lateral columns of the cervical and lumber segments of zitter rats. On the other hand, abnormal TH-immunoreactive fibers with swollen varicosities were located in the anterior and lateral funiculus of lumbar and sacral segments of these mutant rats. The present results suggest that the degeneration patterns differ between catecholaminergic and serotonergic fibers in aged-zitter rats.
収録刊行物
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- Acta Histochemica et Cytochemica
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Acta Histochemica et Cytochemica 32 (4), 341-344, 1999
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詳細情報 詳細情報について
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- CRID
- 1390282679839357184
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- NII論文ID
- 110003147045
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- NII書誌ID
- AA00508022
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- ISSN
- 13475800
- 00445991
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- 本文言語コード
- en
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- データソース種別
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- JaLC
- Crossref
- NDL-Digital
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可