Single Nucleotide Polymorphisms (SNPs) Detected in the gbpC Gene Coding Region of Streptococcus mutans

• Sato Yutaka

  Department of Biochemistry, Tokyo Dental College Oral Health Science Center, Tokyo Dental College

• Okamoto-Shibayama Kazuko

  Department of Biochemistry, Tokyo Dental College Oral Health Science Center, Tokyo Dental College

• Kagami Akiyoshi

  Department of Biochemistry, Tokyo Dental College Oral Health Science Center, Tokyo Dental College

• Yamamoto Yasuhito

  Department of Biochemistry, Tokyo Dental College Oral Health Science Center, Tokyo Dental College

• Kizaki Harutoshi

  Department of Biochemistry, Tokyo Dental College Oral Health Science Center, Tokyo Dental College

抄録

Streptococcus mutans glucan-binding protein C encoded by the gbpC gene is an important virulent factor in human dental caries. However, a nonsense mutation and several nucleotide substitutions in the gbpC gene have been detected in strain GS-5. Therefore, gbpC nucleotide sequences from 17 additional S. mutans strains were determined and single nucleotide polymorphisms were detected. Both conserved and polymorphic regions of the gbpC gene will be useful for estimation of functional domains of GbpC protein and identification of S. mutans strains.

収録刊行物

• Journal of Oral Biosciences

  Journal of Oral Biosciences 47 (2), 171-174, 2005

  歯科基礎医学会

キーワード

• <i>Streptococcus mutans</i>
• glucan-binding protein C
• the <i>gbpC</i> gene
• single nucleotide polymorphisms (SNPs)

詳細情報

• CRID: 1390282680190734848
• NII論文ID: 130004475615
• NII論文ID: 110003166668
• NII書誌ID: AA11896386
• DOI: 10.2330/joralbiosci.47.171
• ISSN: 18803865
• ISSN: 13490079
• Web Site: https://search.jamas.or.jp/link/ui/2006074331
• 本文言語コード: en
• データソース種別:
  • JaLC
  • Crossref
  • CiNii Articles
• 抄録ライセンスフラグ: 使用不可