ラット血清脂質濃度および盲腸内フローラに及ぼすヒアルロン酸の影響

書誌事項

タイトル別名
  • Effect of Hyaluronic Acid on the Levels of Serum Lipids and Cecal Microflora in Rats
  • ラット ケッセイ シシツ ノウド オヨビ モウチョウ ナイ フローラ ニ オヨボス ヒアルロンサン ノ エイキョウ

この論文をさがす

抄録

The effects of hyaluronic acid were determined on the serum and liver lipid levels and cecal microflora of rats. Male Wistar rats were fed on a control diet containing cholesterol (control diet) and on an experimental diet containing either 0.5% or 2.0% hyaluronic acid plus cholesterol for 60 days.The serum total cholesterol and free-cholesterol levels in the rats fed on the 0.5% or 2.0% hyaluronic acid diet were significantly lower than the levels in the control diet, but the addition of hyaluronic acid to the diets induced no change to the concentration of HDL-cholesterol and triglyceride in the serum.The liver cholesterol, triglyceride and total lipid levels in the rats fed on the 2.0% hyaluronic acid diet were significantly lower than those in the rats fed on the control diet, but these lipid levels were unchanged in the liver of the rats given the 0.5% hyaluronic acid diet. More fecal bile acids were excreted by the hyaluronic acid diet groups than by the control diet group, but content of fecal cholesterol remained unchanged. A microflora examination revealed an increase in the counts of cecal Lactobacillus and Bifidobacterium during the administration of hyaluronic acid in the diet. A 2.0% dietary level of hyaluronic acid significantly increased the counts of Lactobacillus and Bifidobacterium, while the 0.5% dietary level of hyaluronic acid had a much smaller effect. These results suggest that the diets containing hyaluronic acid had a beneficial effect on the level of serum lipids and intestinal microflora.

収録刊行物

  • 日本家政学会誌

    日本家政学会誌 55 (9), 701-706, 2004

    一般社団法人 日本家政学会

被引用文献 (2)*注記

もっと見る

参考文献 (24)*注記

もっと見る

関連プロジェクト

もっと見る

詳細情報

問題の指摘

ページトップへ