A New Method on Bioassay Using Hydra by Image Processing

• AIKAWA Haruki

  Faculty of Engineering, Toyama University

• HANAI Kazumitsu

  Biophysics Laboratory, Kyoto Prefectural University of Medicine

• TSUKADA Akira

  Faculty of Engineering, Toyama University

• KAWARADA Atsushi

  Faculty of Engineering, Toyama University

• SASAKI Kazuo

  Faculty of Engineering, Toyama University

Bibliographic Information

Other Title

• 画像処理によるヒドラを用いたバイオアッセイ法に関する基礎研究

Abstract

Growth factors, which are originally identified as cell growth and cell survival stimulants have been recently recognized as multi-functional bio-active substances. In order to measure the growth factor concentration in the blood or cerebrospinal fluid, a highly sensitive, but non-automatic bio-assay system using ball-formation responses of Hydra tentacles has been used. In the present study, we developed an image processing system which automatically detects ball-formation responses. It has been demonstrated that the system, which includes indices of ball formation such as the length of tentacles and the fractal dimension of Hydra successfully detects ball-formation responses in the rate of 94.3%.

Journal

• IEICE technical report. ME and bio cybernetics

  IEICE technical report. ME and bio cybernetics 97 (45), 15-22, 1997-05-16

  The Institute of Electronics, Information and Communication Engineers

Keywords

• Ball-formation response
• Image processing
• Hydra
• Bio-assay
• Cell growth factor

Details

• CRID: 1570854177431737600
• NII Article ID: 110003286722
• NII Book ID: AN1001320X
• Text Lang: ja
• Data Source:
  • CiNii Articles