Measurement of Left Ventricular Chamber and Myocardial Volume in Hypertrophic Cardiomyopathy Patients by ECG-gated Myocardial Perfusion SPECT : Application of a Newly Developed Edge-detection Algorithm

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  • NISHIMURA YOSHIHIRO
    Department of Radiology, National Cardiovascular Center:Department of Medical Engineering, Division of Allied Health Sciences. Osaka University Medical School
  • KATAFUCHI TETSURO
    Department of Radiology, National Cardiovascular Center
  • HIRASE YOSHINORI
    Department of Radiology, National Cardiovascular Center
  • SAGOH MASAYOSHI
    Department of Radiology, National Cardiovascular Center
  • OKA HISASHI
    Department of Radiology, National Cardiovascular Center
  • MORI HIDEAKI
    Siemens-Asahi Medical Technologies, Ltd., Nuclear Medicine Department, Medical Solutions Marketing Division
  • MURASE KENYA
    Department of Medical Engineering, Division of Allied Health Sciences, Osaka University Medical School

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  • 肥大型心筋症における心筋輪郭抽出ソフトウェアMEDcalによる左室容積および心筋重量の算出

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Abstract

Quantitative gated SPECT(QGS)software has been reported to demonstrate inaccurate edge detection in the left ventricular chamber in hypertrophic cardiomyopathy patients. In this study we developed a method to calculate left ventricular volume (LVV) and left myocardial volume (LMV) from gated SPECT data using a newly developed edge-detection algorithm, and we compared it with the QGS method of calculating LVV and LMV in a phantom study. Our method gave more accurate measurements LVV and LMV whereas the QGS method underestimated LMV. Compared with QGS LVV and LMV, our method yielded better results in the phantom study.

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