Three New Sesquiterpenes from the Black Heartwood of <i>Cryptomeria japonica</i>

  • Arihara Shigenobu
    Faculty of Pharmaceutical Sciences, Tokushima Bunri University
  • Umeyama Akemi
    Faculty of Pharmaceutical Sciences, Tokushima Bunri University
  • Bando Shinya
    Faculty of Pharmaceutical Sciences, Tokushima Bunri University
  • Imoto Shinji
    Faculty of Pharmaceutical Sciences, Tokushima Bunri University
  • Ono Mikako
    Faculty of Pharmaceutical Sciences, Tokushima Bunri University
  • Yoshikawa Kazuko
    Faculty of Pharmaceutical Sciences, Tokushima Bunri University

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  • Three New Sesquiterpenes from the Black Heartwood of Cryptomeria japonica

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Abstract

Three new sesquiterpenes, (4S)-2,6,10-bisaboratrien-4-ol-1-one (1), 1,8-epoxy-1(6),2,4,7,10-bisaborapenta-en-4-ol (2), and 1-methoxy-4-cadinene (3) have been isolated from the black heartwood of Cryptomeria japonica. Compounds 1 and 2 were designated sugikurojinols A and B, respectively, and the structures of compounds 1—3 were established by extensive NMR experiments. Compounds 1 and 2 were also examined for antibacterial activity against Staphylococcus aureus and Escherichia coli, and for termiticidal activity against Coptotermes formosanus SHIRAKI.

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