Total Synthesis and Biosynthesis of the Paraherquamides: An Intriguing Story of the Biological Diels–Alder Construction

• Williams Robert Michael

  Contribution from the Department of Chemistry, Colorado State University

書誌事項

タイトル別名

• Total Synthesis and Biosynthesis of the Paraherquamides: An Intriguing Story of the Biological Diels–Alder Construction

抄録

The syntheses and biosyntheses of the paraherquamide and brevianamide families of prenylated indole-derived alkaloids are reviewed. It has been proposed that the unique bicyclo[2.2.2]diazaoctan ring system that is common to this family of natural products, arises by a biological intramolecular Diels–Alder cycloaddition reaction. Both synthetic approaches and total syntheses of several members of this family of natural products are reviewed. The biosynthesis of these alkaloids has also constituted an active area of research and the current state of knowledge on the biosynthesis of these natural products are reviewed.

収録刊行物

• ＣＨＥＭＩＣＡＬ　＆　ＰＨＡＲＭＡＣＥＵＴＩＣＡＬ　ＢＵＬＬＥＴＩＮ

  ＣＨＥＭＩＣＡＬ　＆　ＰＨＡＲＭＡＣＥＵＴＩＣＡＬ　ＢＵＬＬＥＴＩＮ 50 (6), 711-740, 2002

  公益社団法人 日本薬学会

キーワード

• paraherquamide
• marcfortine
• brevianamide
• asperparaline
• biological Diels–Alder
• asymmetric synthesis
• biosynthesis

詳細情報

• CRID: 1390001204164135296
• NII論文ID: 110003616235
• NII書誌ID: AA00602100
• DOI: 10.1248/cpb.50.711
• COI: 1:CAS:528:DC%2BD38XkvFOltrg%3D
• ISSN: 13475223
• ISSN: 00092363
• NDL書誌ID: 6175940
• PubMed: 12045324
• Web Site: https://ndlsearch.ndl.go.jp/books/R000000004-I6175940
• Web Site: https://www.jstage.jst.go.jp/article/cpb/50/6/50_6_711/_pdf
• 本文言語コード: en
• データソース種別:
  • JaLC
  • NDL
  • Crossref
  • PubMed
  • CiNii Articles
• 抄録ライセンスフラグ: 使用不可