Thiation of Oxindoles

• 日野 亨

• 常岡 和子

• 中川 昌子

• 赤星 三弥

抄録

The thiation of methyl substituted oxindoles (I) with phosphorous pentasulfide gave the corresponding 2-indolinethiones (II). The 2-indolinethione (II) having more than one hydrogen at 3-position, however, were sensitive towards phosphorous pentasulfide to produce the indolic compounds such as III, IV, V and VI. On the other hand the 2-indolinethione (VIII) prepared from VII with phosphorous pentasulfide, was stable towards the reagent. Reactivity of 2-indolinthione (IIb) was compared with the oxindole (Ib) in some reactions including the deuteration at 3-position in deuterochloroform-acetic acid-d₄.

収録刊行物

• ＣＨＥＭＩＣＡＬ　＆　ＰＨＡＲＭＡＣＥＵＴＩＣＡＬ　ＢＵＬＬＥＴＩＮ

  ＣＨＥＭＩＣＡＬ　＆　ＰＨＡＲＭＡＣＥＵＴＩＣＡＬ　ＢＵＬＬＥＴＩＮ 17 (3), 550-558, 1969

  公益社団法人 日本薬学会

キーワード

• Drug Discovery
• General Chemistry
• General Medicine

詳細情報

• CRID: 1390001204169223168
• NII論文ID: 110003620925
• NII書誌ID: AA00602100
• DOI: 10.1248/cpb.17.550
• COI: 1:CAS:528:DyaF1MXktFaqsbc%3D
• ISSN: 13475223
• ISSN: 00092363
• ISSN: http://id.crossref.org/issn/00092363
• Web Site: http://www.jstage.jst.go.jp/article/cpb1958/17/3/17_3_550/_pdf
• Web Site: https://search.jamas.or.jp/link/ui/1970106880
• 本文言語コード: en
• データソース種別:
  • JaLC
  • Crossref
  • CiNii Articles
• 抄録ライセンスフラグ: 使用不可