Synthesis of Spiro [4-hydroxycyclohexane-1, 4'-2', 3'-dihydm-6'-methoxy-1'-substituted-2'-methy1-1'<I>H</I>-isoquinoline]

• SHIRAI HIDEAKI

  Faculty of Pharmaceutical Sciences, Nagoya City University

• YASHIRO TAMOTSU

  Faculty of Pharmaceutical Sciences, Nagoya City University

• AOYAMA TAIKI

  Faculty of Pharmaceutical Sciences, Nagoya City University

抄録

For the purpose of testing the biological activity, some galanthamine related compounds, spiro [4-hydroxycyclohexane-1, 4'-2', 3'-dihydro-6'-methoxy-1'-substituted-2'-methy1-1'H-isoquinoline](IIIa, b, c) were synthesized by the application of the Bischler-Napieralski cyclization on the N-acyl compounds (VIIa, b, c).

収録刊行物

• ＣＨＥＭＩＣＡＬ　＆　ＰＨＡＲＭＡＣＥＵＴＩＣＡＬ　ＢＵＬＬＥＴＩＮ

  ＣＨＥＭＩＣＡＬ　＆　ＰＨＡＲＭＡＣＥＵＴＩＣＡＬ　ＢＵＬＬＥＴＩＮ 20 (1), 41-46, 1972

  公益社団法人 日本薬学会

キーワード

• Drug Discovery
• General Chemistry
• General Medicine

詳細情報

• CRID: 1390001204173257472
• NII論文ID: 110003621142
• NII書誌ID: AA00602100
• DOI: 10.1248/cpb.20.41
• ISSN: 13475223
• ISSN: 00092363
• Web Site: http://www.jstage.jst.go.jp/article/cpb1958/20/1/20_1_41/_pdf
• Web Site: https://search.jamas.or.jp/link/ui/1972087520
• 本文言語コード: en
• データソース種別:
  • JaLC
  • Crossref
  • CiNii Articles
• 抄録ライセンスフラグ: 使用不可