Studies on the Activities of Tannins and Related Compounds of Medicinal Plants and Drugs. III. Effects of Various Tannins and Related Compounds on Adrenocorticotropic Hormon-induced Lipolysis and Insulin-induced Lipogenesis from Glucose in Fat Cells. (2)

  • 木村 善行
    2nd Department of Medical Biochemistry, School of Medicine, Ehime University
  • 奥田 拓道
    2nd Department of Medical Biochemistry, School of Medicine, Ehime University
  • 奥田 拓男
    Faculty of Pharmaceutical Sciences, Okayama University
  • 吉田 隆志
    Faculty of Pharmaceutical Sciences, Okayama University
  • 波多野 力
    Faculty of Pharmaceutical Sciences, Okayama University
  • 有地 滋
    The Research Institute of Oriental Medicine, Kinki University

この論文をさがす

抄録

The effects of various tannins and related compounds on the actions of adrenocorticotropic hormone (ACTH) and insulin in fat cells isolated from rats were investigated. Hydrolyzable tannins such as geraniin, mallotusinic acid, chebulinic acid and chebulagic acid enhanced the ACTH-induced lipolysis at the concentration of 20 μg/ml or 5 μg/ml. On the other hand, these hydrolyzable tannins had no effect on the insulin-stimulated lipogenesis from glucose. Condensed tannins such as Ss-tannin 1 and RSF-tannin H showed weak inhibitory effects on the ACTH-induced lipolysis, while they enhanced the insulin-stimulated lipogenesis from glucose. Based on these results, the relationship between the structures and physiological actions of these tannins is discussed.

収録刊行物

キーワード

詳細情報 詳細情報について

問題の指摘

ページトップへ