Highly Stereocontrolled Total Synthesis of the Polyether Antibiotic Salinomycin. IV. Chemical Degradation of Salinomycin for the Structure Confirmation of Synthesic Key Intermediates

• 堀田 清

  Faculty of Pharmaceutical Sciences, Hokkaido University

• 長戸 哲

  Faculty of Pharmaceutical Sciences, Hokkaido University

• 及川 裕二

  Faculty of Pharmaceutical Sciences, Hokkaido University

• 米光 宰

  Faculty of Pharmaceutical Sciences, Hokkaido University

抄録

In order to confirm the structures of some key intermediates employed in the total synthesis of salinomycin (1), natural 1 was cleaved into C1-C9,C10-C30,C10-C17,C21-C30,and C19-C30 segments.

収録刊行物

• Chemical & pharmaceutical bulletin

  Chemical & pharmaceutical bulletin 37 (7), 1726-1730, 1989-07-25

  公益社団法人日本薬学会

キーワード

• polyether antibiotic
• salinomycin
• chemical degradation
• chemical correlation
• retro-aldol reaction

詳細情報

• CRID: 1574231877205302400
• NII論文ID: 110003627846
• NII書誌ID: AA00602100
• ISSN: 00092363
• 本文言語コード: en
• データソース種別:
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