Synthesis of 1-Benzometalloles Containing Group 14,15,and 16 Heavier Elements via a Common Dilithiostyrene Intermediate
Search this Article
The Group 14 (Si, Ge, and Sn), Group 15 (P, As, Sb, and Bi), and Group 16 (Se and Te) 2-trimethylsilyl-1-benzometalloles (7) were prepared by the reaction of the corresponding metal reagents with β, o-dilithio-β-trimethyl-silylstyrene intermediate (6), which was derived from phenylacetylene or o-bromoiodobenzene via three steps. The trimethylsilyl group in 7 could be readily removed by treatment with tetrabutylammonium fluoride to give the C-unsubstituted 1-banzometalloles (10).
- Chem. Pharm. Bull.
Chem. Pharm. Bull. 42, 1437-1441, 1994
The Pharmaceutical Society of Japan