クサウラベニタケの毒性成分の研究(第2報) : 溶血素の精製と溶血条件の検討

DOI Web Site Web Site 被引用文献1件

書誌事項

タイトル別名
  • Studies on the Toxic Components of Rhodophyllus rhodopolius. II. : Partial Purification and Properties of the Hemolysin from Rhodophyllus rhodopolius : Examination on the Condition of the Hemolysis
  • クサウラベニタケの毒性成分の研究-2-溶血素の精製と溶血条件の検討
  • クサウラベニタケ ノ ドクセイ セイブン ノ ケンキュウ 2 ヨウケツソ ノ

この論文をさがす

抄録

A fraction causing diarrhea to mice with a hemolytic activity was previously isolated from the aqueous extract of a poisonous mushroom Rhodophyllus rhodopolius. In order to clarify the relationship between the enterotoxicity and hemolytic activity, the hemolysin was purified. The hemolysin which was partially purified by DEAE-cellulose column chromatography, ammonium sulfate precipitation, and Sephacryl S-300 column chromatography, caused diarrhea and intestinal hemorrhage to suckling mice. The molecular weight of the hemolysin was estimated to be about 40000 by SDS-slab polyacrylamide gel electrophoresis and gel filtration. The hemolytic activity of the hemolysin was observed to be relatively heat-stable in the crude extract and dependent on the temperature and concentration of erythrocytes.

収録刊行物

  • 薬学雑誌

    薬学雑誌 108 (3), 221-225, 1988

    公益社団法人 日本薬学会

被引用文献 (1)*注記

もっと見る

キーワード

詳細情報 詳細情報について

問題の指摘

ページトップへ