Enterococcus faecalis FK-23株加熱死菌体のマウス同系腫瘍に対する抗腫瘍効果 Antitumor Activity of Enterococcus faecalis FK-23 Preparation against Murine Syngeneic Tumors

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抄録

The antitumor activity of a preparation of heat-killed cells of Enterococcus faecalis, FK-23. Intraperitoneal injection of the preparation prolonged the lifespan of C3H/He N mice which were intraperitoneally inoculated with MM46 mammary carcinoma. Not only intraperitoneal but also oral administration of the FK-23 preparation inhibited the growth of these carcinomas inoculated intradermally. The tumor-bearing mice produced tumor necrosis factor (TNF) in their sera 2 h after intravenous injection of OK432. This TNF level increased after the mice were fed with food supplemented with the FK-23 preparation. Additionally, the FK-23 preparation inhibited the growth of Meth A fibrosarcoma in cyclophosphamide-treated BALB/c mice.

収録刊行物

  • 薬学雑誌

    薬学雑誌 113(5), p396-399, 1993-05

    公益社団法人日本薬学会

被引用文献:  10件中 1-10件 を表示

各種コード

  • NII論文ID(NAID)
    110003649409
  • NII書誌ID(NCID)
    AN00284903
  • 本文言語コード
    JPN
  • 資料種別
    雑誌論文
  • ISSN
    00316903
  • NDL 記事登録ID
    3831630
  • NDL 刊行物分類
    SD0(薬学)
  • NDL 雑誌分類
    ZS51(科学技術--薬学)
  • NDL 請求記号
    Z19-411
  • データ提供元
    CJP引用  NDL  NII-ELS 
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