人型結核菌体熱水抽出物質に関する研究(第1報)多糖成分の化学構造

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タイトル別名
  • Studies on Hot Water Extract of Mycobacterium tuberculosis. I. Structural Analyses of Polysaccharides
  • 人型結核菌体熱水抽出物質に関する研究-1-多糖成分の化学構造
  • ヒトガタ ケッカク キンタイ ネッスイ チュウシュツ ブッシツ ニカンスルケン

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抄録

The structures of polysaccharides obtained from hot water extract of Mycobacterium tuberculosis strain Aoyama B were investigated. The polysaccharides fractionated by moleculer sieve-, ion exchange- and affinity-chromatographies and ethanol precipitation were analysed. Main polysaccharides clarified from the results are ; 1) arabinomannan in which arabinan core and mannan core coupled alternately, having average molecular weight of about 12000, 2) mannan with many side chains and average molecular weight of about 5000, 3) a mixture of lipoarabinomannan and lipomannan with fatty acid ester of about 18%, 4) acidic lipoglucan consisting of 6-O-methyl-D-glucose, glucose, 3-O-methyl-D-glucose, glyceric acid, and 6-9 moles of lower fatty acid esters, 5) glycogen-like highmolecular glucan, 6) low-molecular mannan and glucan.

収録刊行物

  • 薬学雑誌

    薬学雑誌 101 (8), 713-722, 1981

    公益社団法人 日本薬学会

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